BDBM50035921 CHEMBL3361071

SMILES: Cc1cccc2c(cc(C(=O)c3ccc(Br)cc3)n12)C(O)=O

InChI Key: InChIKey=HODBEEJOHKGJGI-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50035921   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Homo sapiens (Human))	BDBM50035921 (CHEMBL3361071) Show SMILES Cc1cccc2c(cc(C(=O)c3ccc(Br)cc3)n12)C(O)=O Show InChI InChI=1S/C17H12BrNO3/c1-10-3-2-4-14-13(17(21)22)9-15(19(10)14)16(20)11-5-7-12(18)8-6-11/h2-9H,1H3,(H,21,22)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.48E+4	n/a	n/a	n/a	n/a	n/a	n/a
Alexandru Ioan Cuza University Curated by ChEMBL					Assay Description Inhibition of human recombinant farnesyltransferase using octyl-beta-D-glucopyranoside as substrate after 15 mins by fluorescence assay				Bioorg Med Chem Lett 24: 5777-81 (2014) Article DOI: 10.1016/j.bmcl.2014.10.044 BindingDB Entry DOI: 10.7270/Q2W95BTK
					More data for this Ligand-Target Pair