BDBM50035955 5-Trifluoromethyl-1-[4-(3-trifluoromethyl-phenyl)-thiazol-2-yl]-1H-pyrazole-4-carboxylic acid (3-diethylamino-propyl)-amide::CHEMBL336617

SMILES: CCN(CC)CCCNC(=O)c1cnn(-c2nc(cs2)-c2cccc(c2)C(F)(F)F)c1C(F)(F)F

InChI Key: InChIKey=NRTRTGUHADDPRO-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50035955   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Integrin alpha-IIb/beta-3 (Homo sapiens (Human))	BDBM50035955 (5-Trifluoromethyl-1-[4-(3-trifluoromethyl-phenyl)-...) Show SMILES CCN(CC)CCCNC(=O)c1cnn(-c2nc(cs2)-c2cccc(c2)C(F)(F)F)c1C(F)(F)F Show InChI InChI=1S/C22H23F6N5OS/c1-3-32(4-2)10-6-9-29-19(34)16-12-30-33(18(16)22(26,27)28)20-31-17(13-35-20)14-7-5-8-15(11-14)21(23,24)25/h5,7-8,11-13H,3-4,6,9-10H2,1-2H3,(H,29,34)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	400	n/a	n/a	n/a	n/a	n/a	n/a
R. W. Johnson Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of arachidonic acid-induced platelet aggregation				J Med Chem 38: 34-41 (1995) BindingDB Entry DOI: 10.7270/Q29G5NG8
					More data for this Ligand-Target Pair
Integrin alpha-IIb/beta-3 (Homo sapiens (Human))	BDBM50035955 (5-Trifluoromethyl-1-[4-(3-trifluoromethyl-phenyl)-...) Show SMILES CCN(CC)CCCNC(=O)c1cnn(-c2nc(cs2)-c2cccc(c2)C(F)(F)F)c1C(F)(F)F Show InChI InChI=1S/C22H23F6N5OS/c1-3-32(4-2)10-6-9-29-19(34)16-12-30-33(18(16)22(26,27)28)20-31-17(13-35-20)14-7-5-8-15(11-14)21(23,24)25/h5,7-8,11-13H,3-4,6,9-10H2,1-2H3,(H,29,34)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	2.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
R. W. Johnson Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of collagen-induced platelet aggregation				J Med Chem 38: 34-41 (1995) BindingDB Entry DOI: 10.7270/Q29G5NG8
					More data for this Ligand-Target Pair
Integrin alpha-IIb/beta-3 (Homo sapiens (Human))	BDBM50035955 (5-Trifluoromethyl-1-[4-(3-trifluoromethyl-phenyl)-...) Show SMILES CCN(CC)CCCNC(=O)c1cnn(-c2nc(cs2)-c2cccc(c2)C(F)(F)F)c1C(F)(F)F Show InChI InChI=1S/C22H23F6N5OS/c1-3-32(4-2)10-6-9-29-19(34)16-12-30-33(18(16)22(26,27)28)20-31-17(13-35-20)14-7-5-8-15(11-14)21(23,24)25/h5,7-8,11-13H,3-4,6,9-10H2,1-2H3,(H,29,34)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	4.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
R. W. Johnson Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of [125I]fibrinogen binding to human Fibrinogen Receptor.				J Med Chem 38: 34-41 (1995) BindingDB Entry DOI: 10.7270/Q29G5NG8
					More data for this Ligand-Target Pair