BDBM50035958 1-(4-Phenyl-thiazol-2-yl)-5-trifluoromethyl-1H-pyrazole-4-carboxylic acid (3-diethylamino-propyl)-amide::CHEMBL334815

SMILES: CCN(CC)CCCNC(=O)c1cnn(-c2nc(cs2)-c2ccccc2)c1C(F)(F)F

InChI Key: InChIKey=UAUCQXCTBXUMAS-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50035958   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Integrin alpha-IIb/beta-3 (Homo sapiens (Human))	BDBM50035958 (1-(4-Phenyl-thiazol-2-yl)-5-trifluoromethyl-1H-pyr...) Show SMILES CCN(CC)CCCNC(=O)c1cnn(-c2nc(cs2)-c2ccccc2)c1C(F)(F)F Show InChI InChI=1S/C21H24F3N5OS/c1-3-28(4-2)12-8-11-25-19(30)16-13-26-29(18(16)21(22,23)24)20-27-17(14-31-20)15-9-6-5-7-10-15/h5-7,9-10,13-14H,3-4,8,11-12H2,1-2H3,(H,25,30)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
R. W. Johnson Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of [125I]fibrinogen binding to human Fibrinogen Receptor.				J Med Chem 38: 34-41 (1995) BindingDB Entry DOI: 10.7270/Q29G5NG8
					More data for this Ligand-Target Pair