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SMILES: NCCNC(=O)c1cnn(-c2nc(cs2)-c2cccc(c2)C(F)(F)F)c1C(F)(F)F

InChI Key: InChIKey=HMZWFVSXVROBLA-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50035972   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Integrin alpha-IIb/beta-3


(Homo sapiens (Human))		BDBM50035972
PNG
(5-Trifluoromethyl-1-[4-(3-trifluoromethyl-phenyl)-...)
Show SMILES NCCNC(=O)c1cnn(-c2nc(cs2)-c2cccc(c2)C(F)(F)F)c1C(F)(F)F
Show InChI InChI=1S/C17H13F6N5OS/c18-16(19,20)10-3-1-2-9(6-10)12-8-30-15(27-12)28-13(17(21,22)23)11(7-26-28)14(29)25-5-4-24/h1-3,6-8H,4-5,24H2,(H,25,29)
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KEGG

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PC sid
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Similars
PubMed
n/an/a 1.12E+4n/an/an/an/an/an/a



R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Inhibition of thrombin-induced platelet aggregation at 50 uM

J Med Chem 38: 34-41 (1995)


BindingDB Entry DOI: 10.7270/Q29G5NG8
More data for this
Ligand-Target Pair