null
SMILES: OC(=O)C\C(=C\C(O)=O)C(O)=O
InChI Key: InChIKey=GTZCVFVGUGFEME-IWQZZHSRSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
ATP-citrate synthase (Rattus norvegicus) | BDBM50036222 ((1Z)-prop-1-ene-1,2,3-tricarboxylic acid | (Z)-1-p...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Patents Similars | PubMed | >1.00E+6 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Pharmaceuticals Ltd. Curated by ChEMBL | Assay Description Reversible binding potential for rat ATP-Citrate Lyase as carbon-carbon bond cleavage activity in citrate substrate | J Med Chem 38: 537-43 (1995) BindingDB Entry DOI: 10.7270/Q21Z43GM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prolyl 4-hydroxylase (Paramecium bursaria Chlorella virus 1) | BDBM50036222 ((1Z)-prop-1-ene-1,2,3-tricarboxylic acid | (Z)-1-p...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | >1.00E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Oxford Curated by ChEMBL | Assay Description Inhibition of N-terminal His6-tagged recombinant Paramecium bursaria chlorella virus 1 CPH expressed in Escherichia coli Rosetta 2 (DE3) cells pre-in... | Bioorg Med Chem 27: 2405-2412 (2019) Article DOI: 10.1016/j.bmc.2019.01.018 BindingDB Entry DOI: 10.7270/Q2KK9G4R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-ketoglutarate-dependent dioxygenase FTO (Homo sapiens (Human)) | BDBM50036222 ((1Z)-prop-1-ene-1,2,3-tricarboxylic acid | (Z)-1-p...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | >1.00E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Oxford Curated by ChEMBL | Assay Description Inhibition of human hexahistidine-tagged full-length FTO expressed in Escherichia coli BL21 (DE3) using 3-methylthymidine as substrate assessed as in... | J Med Chem 56: 3680-8 (2013) Article DOI: 10.1021/jm400193d BindingDB Entry DOI: 10.7270/Q21V5GBQ | |||||||||||
More data for this Ligand-Target Pair |