BDBM50036419 CHEMBL163805::N-[4-(4-Hydroxy-3-isopropyl-phenoxy)-3,5-dimethyl-phenyl]-N-methyl-oxalamic acid

SMILES: CC(C)c1cc(Oc2c(C)cc(cc2C)N(C)C(=O)C(O)=O)ccc1O

InChI Key: InChIKey=YOOQKVDPTADYCJ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50036419   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
thyroid beta (RAT)	BDBM50036419 (CHEMBL163805 | N-[4-(4-Hydroxy-3-isopropyl-phenoxy...) Show SMILES CC(C)c1cc(Oc2c(C)cc(cc2C)N(C)C(=O)C(O)=O)ccc1O Show InChI InChI=1S/C20H23NO5/c1-11(2)16-10-15(6-7-17(16)22)26-18-12(3)8-14(9-13(18)4)21(5)19(23)20(24)25/h6-11,22H,1-5H3,(H,24,25)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	120	n/a	n/a	n/a	n/a	n/a	n/a
Ciba Pharmaceuticals Curated by ChEMBL					Assay Description In vitro inhibition of the bound [125I]L-T3 rat liver nuclear L-triiodothyronine receptor				J Med Chem 38: 695-707 (1995) BindingDB Entry DOI: 10.7270/Q2T43TRC
					More data for this Ligand-Target Pair