BDBM50036626 CHEMBL3354280

SMILES: COc1ccc(CNc2nc(ncc2C(=O)NCc2ncccn2)N2CCOC[C@H]2CO)cc1Cl

InChI Key: InChIKey=CMPFBGRJUYECDH-MRXNPFEDSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50036626   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cGMP-specific 3',5'-cyclic phosphodiesterase (Canis lupus familiaris)	BDBM50036626 (CHEMBL3354280) Show SMILES COc1ccc(CNc2nc(ncc2C(=O)NCc2ncccn2)N2CCOC[C@H]2CO)cc1Cl |r| Show InChI InChI=1S/C23H26ClN7O4/c1-34-19-4-3-15(9-18(19)24)10-27-21-17(22(33)28-12-20-25-5-2-6-26-20)11-29-23(30-21)31-7-8-35-14-16(31)13-32/h2-6,9,11,16,32H,7-8,10,12-14H2,1H3,(H,28,33)(H,27,29,30)/t16-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>100	n/a	n/a	n/a	n/a	n/a	n/a
Mitsubishi Tanabe Pharma Corporation Curated by ChEMBL					Assay Description Inhibition of dog lungs PDE5 using [3H]cGMP as substrate after 30 mins by scintillation counting analysis				Bioorg Med Chem Lett 24: 5460-5 (2015) Article DOI: 10.1016/j.bmcl.2014.10.008 BindingDB Entry DOI: 10.7270/Q2JS9S1W
					More data for this Ligand-Target Pair