BDBM50036652 CHEMBL3354784

SMILES: CCOC(=O)[C@@]1(Cc2ccccc2)CCc2cnc3c(cnn3c12)-c1ccc(Cl)cc1

InChI Key: InChIKey=YTIMOVZKXDRWIW-RUZDIDTESA-N

Data: 2 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50036652   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glucose-dependent insulinotropic receptor (Mus musculus)	BDBM50036652 (CHEMBL3354784) Show SMILES CCOC(=O)[C@@]1(Cc2ccccc2)CCc2cnc3c(cnn3c12)-c1ccc(Cl)cc1 |r| Show InChI InChI=1S/C25H22ClN3O2/c1-2-31-24(30)25(14-17-6-4-3-5-7-17)13-12-19-15-27-23-21(16-28-29(23)22(19)25)18-8-10-20(26)11-9-18/h3-11,15-16H,2,12-14H2,1H3/t25-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	11	n/a	n/a	n/a	n/a
Genomics Institute of the Novartis Research Foundation Curated by ChEMBL					Assay Description Agonist activity at mouse GPR119 overexpressed in CHO cells assessed as increase in cellular cAMP production by HTRF method				Bioorg Med Chem Lett 24: 5478-83 (2015) Article DOI: 10.1016/j.bmcl.2014.10.010 BindingDB Entry DOI: 10.7270/Q29C7019
					More data for this Ligand-Target Pair
G-protein coupled receptor 119 (GPR119) (Homo sapiens (Human))	BDBM50036652 (CHEMBL3354784) Show SMILES CCOC(=O)[C@@]1(Cc2ccccc2)CCc2cnc3c(cnn3c12)-c1ccc(Cl)cc1 |r| Show InChI InChI=1S/C25H22ClN3O2/c1-2-31-24(30)25(14-17-6-4-3-5-7-17)13-12-19-15-27-23-21(16-28-29(23)22(19)25)18-8-10-20(26)11-9-18/h3-11,15-16H,2,12-14H2,1H3/t25-/m1/s1	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	3	n/a	n/a	n/a	n/a
Genomics Institute of the Novartis Research Foundation Curated by ChEMBL					Assay Description Agonist activity at human GPR119 overexpressed in CHO cells assessed as increase in cellular cAMP production by HTRF method				Bioorg Med Chem Lett 24: 5478-83 (2015) Article DOI: 10.1016/j.bmcl.2014.10.010 BindingDB Entry DOI: 10.7270/Q29C7019
					More data for this Ligand-Target Pair