BDBM50036787 2-Amino-3-(4-hydroxy-2,6-dimethyl-phenyl)-N-[(R)-1-(3-phenyl-propylcarbamoyl)-ethyl]-propionamide::CHEMBL171763
SMILES: C[C@@H](NC(=O)C(N)Cc1c(C)cc(O)cc1C)C(=O)NCCCc1ccccc1
InChI Key: InChIKey=DGIVTTGQFOQCPP-OQHSHRKDSA-N
Data: 5 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Opioid receptors; mu & delta (Rattus norvegicus (rat)) | BDBM50036787 (2-Amino-3-(4-hydroxy-2,6-dimethyl-phenyl)-N-[(R)-1...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 9.60 | n/a | n/a | n/a | n/a | n/a | n/a |
Searle Curated by ChEMBL | Assay Description Inhibitory concentration of the compound was evaluated against delta opioid receptor by the displacement of tritiated DSLET from rat brain membranes | J Med Chem 37: 888-96 (1994) BindingDB Entry DOI: 10.7270/Q27H1HN2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mu-type opioid receptor (Rattus norvegicus (rat)) | BDBM50036787 (2-Amino-3-(4-hydroxy-2,6-dimethyl-phenyl)-N-[(R)-1...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 0.130 | n/a | n/a | n/a | n/a | n/a | n/a |
Searle Curated by ChEMBL | Assay Description Inhibitory concentration of the compound was evaluated against mu opioid receptor by the displacement of tritiated DAMGO from rat brain membranes | J Med Chem 37: 888-96 (1994) BindingDB Entry DOI: 10.7270/Q27H1HN2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mu-type opioid receptor (Rattus norvegicus (rat)) | BDBM50036787 (2-Amino-3-(4-hydroxy-2,6-dimethyl-phenyl)-N-[(R)-1...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 0.130 | n/a | n/a | n/a | n/a | n/a | n/a |
Searle Curated by ChEMBL | Assay Description Inhibitory concentration of the compound was evaluated against mu opioid receptor by the displacement of tritiated DAMGO from rat brain membranes | J Med Chem 37: 888-96 (1994) BindingDB Entry DOI: 10.7270/Q27H1HN2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Opioid receptors; mu & delta (Rattus norvegicus (rat)) | BDBM50036787 (2-Amino-3-(4-hydroxy-2,6-dimethyl-phenyl)-N-[(R)-1...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 8.60 | n/a | n/a | n/a | n/a | n/a | n/a |
Searle Curated by ChEMBL | Assay Description Displacement of [3H]-DSLET from rat brain membrane delta opioid receptor | J Med Chem 37: 888-96 (1994) BindingDB Entry DOI: 10.7270/Q27H1HN2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kappa-type opioid receptor (Rattus norvegicus (rat)) | BDBM50036787 (2-Amino-3-(4-hydroxy-2,6-dimethyl-phenyl)-N-[(R)-1...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 221 | n/a | n/a | n/a | n/a | n/a | n/a |
Searle Curated by ChEMBL | Assay Description Inhibitory concentration of the compound was evaluated against kappa opioid receptor by displacement of tritiated U-69593 from rat brain membranes | J Med Chem 37: 888-96 (1994) BindingDB Entry DOI: 10.7270/Q27H1HN2 | |||||||||||
More data for this Ligand-Target Pair |