BDBM50036789 CHEMBL3354831

SMILES: CC(C)S(=O)(=O)c1c(Cl)ccc(Nc2nc(=O)cc(Cc3ccccc3)[nH]2)c1O

InChI Key: InChIKey=IRMYNVGQVHHOMV-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50036789   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
C-X-C chemokine receptor type 2 (Homo sapiens (Human))	BDBM50036789 (CHEMBL3354831) Show SMILES CC(C)S(=O)(=O)c1c(Cl)ccc(Nc2nc(=O)cc(Cc3ccccc3)[nH]2)c1O Show InChI InChI=1S/C20H20ClN3O4S/c1-12(2)29(27,28)19-15(21)8-9-16(18(19)26)23-20-22-14(11-17(25)24-20)10-13-6-4-3-5-7-13/h3-9,11-12,26H,10H2,1-2H3,(H2,22,23,24,25)	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	398	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity at CXCR2 (unknown origin) by beta-arrestin assay				Bioorg Med Chem Lett 24: 5493-6 (2015) Article DOI: 10.1016/j.bmcl.2014.10.003 BindingDB Entry DOI: 10.7270/Q21V5GKV
					More data for this Ligand-Target Pair