BDBM50036804 CHEMBL3355240

SMILES: CC(C)S(=O)(=O)c1c(Cl)ccc(Nc2nc(=O)cc([nH]2)C2(C)CCC2)c1O

InChI Key: InChIKey=XQCOJZVTCQDWHW-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50036804   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
C-X-C chemokine receptor type 2 (Homo sapiens (Human))	BDBM50036804 (CHEMBL3355240) Show SMILES CC(C)S(=O)(=O)c1c(Cl)ccc(Nc2nc(=O)cc([nH]2)C2(C)CCC2)c1O Show InChI InChI=1S/C18H22ClN3O4S/c1-10(2)27(25,26)16-11(19)5-6-12(15(16)24)20-17-21-13(9-14(23)22-17)18(3)7-4-8-18/h5-6,9-10,24H,4,7-8H2,1-3H3,(H2,20,21,22,23)	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity at CXCR2 (unknown origin) by beta-arrestin assay				Bioorg Med Chem Lett 24: 5493-6 (2015) Article DOI: 10.1016/j.bmcl.2014.10.003 BindingDB Entry DOI: 10.7270/Q21V5GKV
					More data for this Ligand-Target Pair