null

SMILES: O=c1n(CCCCN2CCN(CC2)c2nsc3ccccc23)cnc2ccccc12

InChI Key: InChIKey=KZJJPWMLHGEQSC-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50036925   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50036925 (3-[4-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-bu...) Show SMILES O=c1n(CCCCN2CCN(CC2)c2nsc3ccccc23)cnc2ccccc12 Show InChI InChI=1S/C23H25N5OS/c29-23-18-7-1-3-9-20(18)24-17-28(23)12-6-5-11-26-13-15-27(16-14-26)22-19-8-2-4-10-21(19)30-25-22/h1-4,7-10,17H,5-6,11-16H2	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
Burroughs Wellcome Company Curated by ChEMBL					Assay Description In vitro binding affinity was measured by displacement of [3H]- raclopride from D2 receptor isolated from the striata of male Dawley rats				J Med Chem 37: 2552-63 (1994) BindingDB Entry DOI: 10.7270/Q2G15ZWF
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50036925 (3-[4-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-bu...) Show SMILES O=c1n(CCCCN2CCN(CC2)c2nsc3ccccc23)cnc2ccccc12 Show InChI InChI=1S/C23H25N5OS/c29-23-18-7-1-3-9-20(18)24-17-28(23)12-6-5-11-26-13-15-27(16-14-26)22-19-8-2-4-10-21(19)30-25-22/h1-4,7-10,17H,5-6,11-16H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	0.590	n/a	n/a	n/a	n/a	n/a	n/a
Burroughs Wellcome Company Curated by ChEMBL					Assay Description In vitro binding affinity was measured on serotonergic 5-hydroxytryptamine 1A receptor by displacement of [3H]- tetralin				J Med Chem 37: 2552-63 (1994) BindingDB Entry DOI: 10.7270/Q2G15ZWF
					More data for this Ligand-Target Pair