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SMILES: CC(O)c1cnc([nH]1)[C@@H](C[C@H](O)[C@H](Cc1ccccc1)NC(=O)OC(C)(C)C)Cc1ccccc1

InChI Key: InChIKey=IZBZXMFQVPZEGF-JYJNSPSNSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50037119   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Gag-Pol polyprotein [489-587]


(Human immunodeficiency virus type 1)		BDBM50037119
PNG
(CHEMBL448480 | {(1S,2S,4R)-1-Benzyl-2-hydroxy-4-[5...)
Show SMILES CC(O)c1cnc([nH]1)[C@@H](C[C@H](O)[C@H](Cc1ccccc1)NC(=O)OC(C)(C)C)Cc1ccccc1
Show InChI InChI=1S/C28H37N3O4/c1-19(32)24-18-29-26(30-24)22(15-20-11-7-5-8-12-20)17-25(33)23(16-21-13-9-6-10-14-21)31-27(34)35-28(2,3)4/h5-14,18-19,22-23,25,32-33H,15-17H2,1-4H3,(H,29,30)(H,31,34)/t19?,22-,23+,25+/m1/s1
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MMDB

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PC cid
PC sid
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Similars
PubMed
 1.33E+4n/an/an/an/an/an/an/an/a



SmithKline Beecham Pharmaceuticals

Curated by ChEMBL


Assay Description
Apparent inhibition constant against recombinant HIV-1 protease

J Med Chem 37: 3100-7 (1994)


BindingDB Entry DOI: 10.7270/Q2T72GG9
More data for this
Ligand-Target Pair