BDBM50037245 CHEMBL288300::Heptanoic acid [2-(7-methoxy-naphthalen-1-yl)-ethyl]-amide
SMILES: CCCCCCC(=O)NCCc1cccc2ccc(OC)cc12
InChI Key: InChIKey=GGUICPRYMICIBA-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Melatonin receptor (Homo sapiens (Human)) | BDBM50037245 (CHEMBL288300 | Heptanoic acid [2-(7-methoxy-naphth...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ d'Orl£ans Curated by ChEMBL | Assay Description Melatonin receptor type 1A binding affinity measured using 2-[125I]iodomelatonin on ovine pars tuberalis membrane homogenates. | J Med Chem 41: 4453-65 (1998) Article DOI: 10.1021/jm980026p BindingDB Entry DOI: 10.7270/Q2B27WHJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Melatonin receptor (Homo sapiens (Human)) | BDBM50037245 (CHEMBL288300 | Heptanoic acid [2-(7-methoxy-naphth...) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Institut de Chimie Pharmaceutique Curated by ChEMBL | Assay Description Monophasic inhibitory concentration against melatonin receptor was measured on ovine pars tuberalis membrane. | J Med Chem 37: 3231-9 (1994) Article DOI: 10.1021/jm00046a006 BindingDB Entry DOI: 10.7270/Q2S75K1J | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Melatonin receptor (Homo sapiens (Human)) | BDBM50037245 (CHEMBL288300 | Heptanoic acid [2-(7-methoxy-naphth...) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | 2.60E+3 | n/a | n/a | n/a | n/a | n/a |
Institut de Chimie Pharmaceutique Curated by ChEMBL | Assay Description Binding affinity to melatonin receptor measured on ovine pars tuberalis membrane | J Med Chem 37: 3231-9 (1994) Article DOI: 10.1021/jm00046a006 BindingDB Entry DOI: 10.7270/Q2S75K1J | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Melatonin receptor (Homo sapiens (Human)) | BDBM50037245 (CHEMBL288300 | Heptanoic acid [2-(7-methoxy-naphth...) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | 2.30 | n/a | n/a | n/a | n/a | n/a |
Universite de Lille Curated by ChEMBL | Assay Description Binding affinity against Melatonin receptor using ovine pars tuberalis membranes of the pituitary. | J Med Chem 35: 1484-6 (1992) BindingDB Entry DOI: 10.7270/Q2B85BB0 | |||||||||||
More data for this Ligand-Target Pair |