BDBM50037653 3-(2,4-Difluoro-phenyl)-1-[5-(4,5-diphenyl-1H-imidazol-2-ylsulfanyl)-pentyl]-1-propyl-urea::CHEMBL119081

SMILES: CCCN(CCCCCSc1nc(c([nH]1)-c1ccccc1)-c1ccccc1)C(=O)Nc1ccc(F)cc1F

InChI Key: InChIKey=NIFGUIVWSCIQGV-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50037653   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sterol O-acyltransferase, Soat (Rattus norvegicus)	BDBM50037653 (3-(2,4-Difluoro-phenyl)-1-[5-(4,5-diphenyl-1H-imid...) Show SMILES CCCN(CCCCCSc1nc(c([nH]1)-c1ccccc1)-c1ccccc1)C(=O)Nc1ccc(F)cc1F Show InChI InChI=1S/C30H32F2N4OS/c1-2-18-36(30(37)33-26-17-16-24(31)21-25(26)32)19-10-5-11-20-38-29-34-27(22-12-6-3-7-13-22)28(35-29)23-14-8-4-9-15-23/h3-4,6-9,12-17,21H,2,5,10-11,18-20H2,1H3,(H,33,37)(H,34,35)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Merck Research Laboratories Curated by ChEMBL					Assay Description In vitro inhibition of Acyl coenzyme A:cholesterol acyltransferase in rat hepatic microsomes				J Med Chem 37: 3511-22 (1994) BindingDB Entry DOI: 10.7270/Q2MK6BXK
					More data for this Ligand-Target Pair