BDBM50037857 2-{(3R,5R)-3-[3-(3-Chloro-phenyl)-ureido]-2-oxo-5-phenyl-2,3,4,5-tetrahydro-benzo[b]azepin-1-yl}-N-(1-methyl-1-phenyl-ethyl)-acetamide::CHEMBL446682

SMILES: CC(C)(NC(=O)CN1c2ccccc2[C@H](C[C@@H](NC(=O)Nc2cccc(Cl)c2)C1=O)c1ccccc1)c1ccccc1

InChI Key: InChIKey=DVASHPOLPKOKGD-FQLXRVMXSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50037857   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Gastrin/cholecystokinin type B receptor (Homo sapiens (Human))	BDBM50037857 (2-{(3R,5R)-3-[3-(3-Chloro-phenyl)-ureido]-2-oxo-5-...) Show SMILES CC(C)(NC(=O)CN1c2ccccc2[C@H](C[C@@H](NC(=O)Nc2cccc(Cl)c2)C1=O)c1ccccc1)c1ccccc1 Show InChI InChI=1S/C34H33ClN4O3/c1-34(2,24-14-7-4-8-15-24)38-31(40)22-39-30-19-10-9-18-27(30)28(23-12-5-3-6-13-23)21-29(32(39)41)37-33(42)36-26-17-11-16-25(35)20-26/h3-20,28-29H,21-22H2,1-2H3,(H,38,40)(H2,36,37,42)/t28-,29-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	10.6	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description In vitro affinity to the cholecystokinin type B receptor in guinea pig cortex assayed using [125I]-BH-CCK-8 as radioligand				J Med Chem 37: 3789-811 (1994) BindingDB Entry DOI: 10.7270/Q2KK99TN
					More data for this Ligand-Target Pair
Cholecystokinin receptor type A (Cavia porcellus)	BDBM50037857 (2-{(3R,5R)-3-[3-(3-Chloro-phenyl)-ureido]-2-oxo-5-...) Show SMILES CC(C)(NC(=O)CN1c2ccccc2[C@H](C[C@@H](NC(=O)Nc2cccc(Cl)c2)C1=O)c1ccccc1)c1ccccc1 Show InChI InChI=1S/C34H33ClN4O3/c1-34(2,24-14-7-4-8-15-24)38-31(40)22-39-30-19-10-9-18-27(30)28(23-12-5-3-6-13-23)21-29(32(39)41)37-33(42)36-26-17-11-16-25(35)20-26/h3-20,28-29H,21-22H2,1-2H3,(H,38,40)(H2,36,37,42)/t28-,29-/m1/s1	PDB MMDB Reactome pathway UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	460	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description In vitro binding affinity for the cholecystokinin type A receptor in guinea pig pancreas assayed using [125I]-BH-CCK-8 as radioligand				J Med Chem 37: 3789-811 (1994) BindingDB Entry DOI: 10.7270/Q2KK99TN
					More data for this Ligand-Target Pair