BDBM50038419 CHEMBL50112::N-(1-Benzyl-piperidin-4-yl)-4-iodo-benzamide

SMILES: Ic1ccc(cc1)C(=O)NC1CCN(Cc2ccccc2)CC1

InChI Key: InChIKey=HELCSESNNDZLFM-UHFFFAOYSA-N

Data: 2 KI

PDB links: 1 PDB ID matches this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50038419   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50038419 (CHEMBL50112 | N-(1-Benzyl-piperidin-4-yl)-4-iodo-b...) Show SMILES Ic1ccc(cc1)C(=O)NC1CCN(Cc2ccccc2)CC1 Show InChI InChI=1S/C19H21IN2O/c20-17-8-6-16(7-9-17)19(23)21-18-10-12-22(13-11-18)14-15-4-2-1-3-5-15/h1-9,18H,10-14H2,(H,21,23)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	PDB PubMed	1.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
George Washington University Medical Center Curated by ChEMBL					Assay Description Binding affinity against sigma-1 receptor in guinea pig brain using [3H]-(+)-pentazocine as radioligand.				J Med Chem 37: 1737-9 (1994) BindingDB Entry DOI: 10.7270/Q2VX0FJ7
					More data for this Ligand-Target Pair				3D Structure (crystal)
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50038419 (CHEMBL50112 | N-(1-Benzyl-piperidin-4-yl)-4-iodo-b...) Show SMILES Ic1ccc(cc1)C(=O)NC1CCN(Cc2ccccc2)CC1 Show InChI InChI=1S/C19H21IN2O/c20-17-8-6-16(7-9-17)19(23)21-18-10-12-22(13-11-18)14-15-4-2-1-3-5-15/h1-9,18H,10-14H2,(H,21,23)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	PubMed	382	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
George Washington University Medical Center Curated by ChEMBL					Assay Description Binding affinity against D-2 dopamine receptor in rat brain membranes using [3H]-(-)-sulpiride as radioligand.				J Med Chem 37: 1737-9 (1994) BindingDB Entry DOI: 10.7270/Q2VX0FJ7
					More data for this Ligand-Target Pair