BDBM50038423 CHEMBL3361128

SMILES: Oc1ccc(\C=C2\Oc3ccccc3C2=O)cc1O

InChI Key: InChIKey=HCBULGQMULJTCM-RIYZIHGNSA-N

Data: 18 IC50  2 Kd

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 20 hits for monomerid = 50038423   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP-dependent protein kinase (PKA) (Homo sapiens (Human))	BDBM50038423 (CHEMBL3361128) Show SMILES Oc1ccc(\C=C2\Oc3ccccc3C2=O)cc1O Show InChI InChI=1S/C15H10O4/c16-11-6-5-9(7-12(11)17)8-14-15(18)10-3-1-2-4-13(10)19-14/h1-8,16-17H/b14-8+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Fudan University Curated by ChEMBL					Assay Description Inhibition of recombinant PRKACA (unknown origin) after 60 mins by z'-lyte kinase assay				Eur J Med Chem 89: 310-9 (2014) Article DOI: 10.1016/j.ejmech.2014.10.044 BindingDB Entry DOI: 10.7270/Q2JQ12NJ
					More data for this Ligand-Target Pair
Aurora kinase B (Homo sapiens (Human))	BDBM50038423 (CHEMBL3361128) Show SMILES Oc1ccc(\C=C2\Oc3ccccc3C2=O)cc1O Show InChI InChI=1S/C15H10O4/c16-11-6-5-9(7-12(11)17)8-14-15(18)10-3-1-2-4-13(10)19-14/h1-8,16-17H/b14-8+	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	735	n/a	n/a	n/a	n/a	n/a	n/a
Fudan University Curated by ChEMBL					Assay Description Inhibition of recombinant AURKB (unknown origin) after 60 mins by z'-lyte kinase assay				Eur J Med Chem 89: 310-9 (2014) Article DOI: 10.1016/j.ejmech.2014.10.044 BindingDB Entry DOI: 10.7270/Q2JQ12NJ
					More data for this Ligand-Target Pair
p21-Activated kinase 2 (PAK2) (Homo sapiens (Human))	BDBM50038423 (CHEMBL3361128) Show SMILES Oc1ccc(\C=C2\Oc3ccccc3C2=O)cc1O Show InChI InChI=1S/C15H10O4/c16-11-6-5-9(7-12(11)17)8-14-15(18)10-3-1-2-4-13(10)19-14/h1-8,16-17H/b14-8+	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Fudan University Curated by ChEMBL					Assay Description Inhibition of recombinant PAK2 (unknown origin) after 60 mins by z'-lyte kinase assay				Eur J Med Chem 89: 310-9 (2014) Article DOI: 10.1016/j.ejmech.2014.10.044 BindingDB Entry DOI: 10.7270/Q2JQ12NJ
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 1 (Homo sapiens (Human))	BDBM50038423 (CHEMBL3361128) Show SMILES Oc1ccc(\C=C2\Oc3ccccc3C2=O)cc1O Show InChI InChI=1S/C15H10O4/c16-11-6-5-9(7-12(11)17)8-14-15(18)10-3-1-2-4-13(10)19-14/h1-8,16-17H/b14-8+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Fudan University Curated by ChEMBL					Assay Description Inhibition of recombinant MAPK1 (unknown origin) after 60 mins by z'-lyte kinase assay				Eur J Med Chem 89: 310-9 (2014) Article DOI: 10.1016/j.ejmech.2014.10.044 BindingDB Entry DOI: 10.7270/Q2JQ12NJ
					More data for this Ligand-Target Pair
Insulin-like growth factor I receptor (Homo sapiens (Human))	BDBM50038423 (CHEMBL3361128) Show SMILES Oc1ccc(\C=C2\Oc3ccccc3C2=O)cc1O Show InChI InChI=1S/C15H10O4/c16-11-6-5-9(7-12(11)17)8-14-15(18)10-3-1-2-4-13(10)19-14/h1-8,16-17H/b14-8+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Fudan University Curated by ChEMBL					Assay Description Inhibition of recombinant IGF1R (unknown origin) after 60 mins by z'-lyte kinase assay				Eur J Med Chem 89: 310-9 (2014) Article DOI: 10.1016/j.ejmech.2014.10.044 BindingDB Entry DOI: 10.7270/Q2JQ12NJ
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50038423 (CHEMBL3361128) Show SMILES Oc1ccc(\C=C2\Oc3ccccc3C2=O)cc1O Show InChI InChI=1S/C15H10O4/c16-11-6-5-9(7-12(11)17)8-14-15(18)10-3-1-2-4-13(10)19-14/h1-8,16-17H/b14-8+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Fudan University Curated by ChEMBL					Assay Description Inhibition of recombinant EGFR (unknown origin) after 60 mins by z'-lyte kinase assay				Eur J Med Chem 89: 310-9 (2014) Article DOI: 10.1016/j.ejmech.2014.10.044 BindingDB Entry DOI: 10.7270/Q2JQ12NJ
					More data for this Ligand-Target Pair
Casein kinase I isoform alpha (Homo sapiens (Human))	BDBM50038423 (CHEMBL3361128) Show SMILES Oc1ccc(\C=C2\Oc3ccccc3C2=O)cc1O Show InChI InChI=1S/C15H10O4/c16-11-6-5-9(7-12(11)17)8-14-15(18)10-3-1-2-4-13(10)19-14/h1-8,16-17H/b14-8+	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.88E+4	n/a	n/a	n/a	n/a	n/a	n/a
Fudan University Curated by ChEMBL					Assay Description Inhibition of recombinant CK1 alpha1 (unknown origin) after 60 mins by z'-lyte kinase assay				Eur J Med Chem 89: 310-9 (2014) Article DOI: 10.1016/j.ejmech.2014.10.044 BindingDB Entry DOI: 10.7270/Q2JQ12NJ
					More data for this Ligand-Target Pair
RAC-alpha serine/threonine-protein kinase (Homo sapiens (Human))	BDBM50038423 (CHEMBL3361128) Show SMILES Oc1ccc(\C=C2\Oc3ccccc3C2=O)cc1O Show InChI InChI=1S/C15H10O4/c16-11-6-5-9(7-12(11)17)8-14-15(18)10-3-1-2-4-13(10)19-14/h1-8,16-17H/b14-8+	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.86E+4	n/a	n/a	n/a	n/a	n/a	n/a
Fudan University Curated by ChEMBL					Assay Description Inhibition of recombinant AKT1 (unknown origin) after 60 mins by z'-lyte kinase assay				Eur J Med Chem 89: 310-9 (2014) Article DOI: 10.1016/j.ejmech.2014.10.044 BindingDB Entry DOI: 10.7270/Q2JQ12NJ
					More data for this Ligand-Target Pair
Aurora kinase B (Homo sapiens (Human))	BDBM50038423 (CHEMBL3361128) Show SMILES Oc1ccc(\C=C2\Oc3ccccc3C2=O)cc1O Show InChI InChI=1S/C15H10O4/c16-11-6-5-9(7-12(11)17)8-14-15(18)10-3-1-2-4-13(10)19-14/h1-8,16-17H/b14-8+	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	3.10	n/a	n/a	n/a	n/a	n/a
Fudan University Curated by ChEMBL					Assay Description Binding affinity to AURKB (unknown origin)				Eur J Med Chem 89: 310-9 (2014) Article DOI: 10.1016/j.ejmech.2014.10.044 BindingDB Entry DOI: 10.7270/Q2JQ12NJ
					More data for this Ligand-Target Pair
Aurora kinase A (Homo sapiens (Human))	BDBM50038423 (CHEMBL3361128) Show SMILES Oc1ccc(\C=C2\Oc3ccccc3C2=O)cc1O Show InChI InChI=1S/C15H10O4/c16-11-6-5-9(7-12(11)17)8-14-15(18)10-3-1-2-4-13(10)19-14/h1-8,16-17H/b14-8+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	1.30	n/a	n/a	n/a	n/a	n/a
Fudan University Curated by ChEMBL					Assay Description Binding affinity to AURKA (unknown origin)				Eur J Med Chem 89: 310-9 (2014) Article DOI: 10.1016/j.ejmech.2014.10.044 BindingDB Entry DOI: 10.7270/Q2JQ12NJ
					More data for this Ligand-Target Pair
Protein kinase C alpha type (Homo sapiens (Human))	BDBM50038423 (CHEMBL3361128) Show SMILES Oc1ccc(\C=C2\Oc3ccccc3C2=O)cc1O Show InChI InChI=1S/C15H10O4/c16-11-6-5-9(7-12(11)17)8-14-15(18)10-3-1-2-4-13(10)19-14/h1-8,16-17H/b14-8+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.68E+4	n/a	n/a	n/a	n/a	n/a	n/a
Fudan University Curated by ChEMBL					Assay Description Inhibition of recombinant PKC alpha (unknown origin) after 60 mins by z'-lyte kinase assay				Eur J Med Chem 89: 310-9 (2014) Article DOI: 10.1016/j.ejmech.2014.10.044 BindingDB Entry DOI: 10.7270/Q2JQ12NJ
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase Nek1 (Homo sapiens (Human))	BDBM50038423 (CHEMBL3361128) Show SMILES Oc1ccc(\C=C2\Oc3ccccc3C2=O)cc1O Show InChI InChI=1S/C15H10O4/c16-11-6-5-9(7-12(11)17)8-14-15(18)10-3-1-2-4-13(10)19-14/h1-8,16-17H/b14-8+	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.15E+4	n/a	n/a	n/a	n/a	n/a	n/a
Fudan University Curated by ChEMBL					Assay Description Inhibition of recombinant NEK1 (unknown origin) after 60 mins by z'-lyte kinase assay				Eur J Med Chem 89: 310-9 (2014) Article DOI: 10.1016/j.ejmech.2014.10.044 BindingDB Entry DOI: 10.7270/Q2JQ12NJ
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50038423 (CHEMBL3361128) Show SMILES Oc1ccc(\C=C2\Oc3ccccc3C2=O)cc1O Show InChI InChI=1S/C15H10O4/c16-11-6-5-9(7-12(11)17)8-14-15(18)10-3-1-2-4-13(10)19-14/h1-8,16-17H/b14-8+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.96E+3	n/a	n/a	n/a	n/a	n/a	n/a
Fudan University Curated by ChEMBL					Assay Description Inhibition of recombinant KDR (unknown origin) after 60 mins by z'-lyte kinase assay				Eur J Med Chem 89: 310-9 (2014) Article DOI: 10.1016/j.ejmech.2014.10.044 BindingDB Entry DOI: 10.7270/Q2JQ12NJ
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 3 (Homo sapiens (Human))	BDBM50038423 (CHEMBL3361128) Show SMILES Oc1ccc(\C=C2\Oc3ccccc3C2=O)cc1O Show InChI InChI=1S/C15H10O4/c16-11-6-5-9(7-12(11)17)8-14-15(18)10-3-1-2-4-13(10)19-14/h1-8,16-17H/b14-8+	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.19E+3	n/a	n/a	n/a	n/a	n/a	n/a
Fudan University Curated by ChEMBL					Assay Description Inhibition of recombinant FLT4 (unknown origin) after 60 mins by z'-lyte kinase assay				Eur J Med Chem 89: 310-9 (2014) Article DOI: 10.1016/j.ejmech.2014.10.044 BindingDB Entry DOI: 10.7270/Q2JQ12NJ
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase Aurora-C (Homo sapiens (Human))	BDBM50038423 (CHEMBL3361128) Show SMILES Oc1ccc(\C=C2\Oc3ccccc3C2=O)cc1O Show InChI InChI=1S/C15H10O4/c16-11-6-5-9(7-12(11)17)8-14-15(18)10-3-1-2-4-13(10)19-14/h1-8,16-17H/b14-8+	PDB NCI pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.75E+3	n/a	n/a	n/a	n/a	n/a	n/a
Fudan University Curated by ChEMBL					Assay Description Inhibition of recombinant AURKC (unknown origin) after 60 mins by z'-lyte kinase assay				Eur J Med Chem 89: 310-9 (2014) Article DOI: 10.1016/j.ejmech.2014.10.044 BindingDB Entry DOI: 10.7270/Q2JQ12NJ
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor alpha (Homo sapiens (Human))	BDBM50038423 (CHEMBL3361128) Show SMILES Oc1ccc(\C=C2\Oc3ccccc3C2=O)cc1O Show InChI InChI=1S/C15H10O4/c16-11-6-5-9(7-12(11)17)8-14-15(18)10-3-1-2-4-13(10)19-14/h1-8,16-17H/b14-8+	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.04E+3	n/a	n/a	n/a	n/a	n/a	n/a
Fudan University Curated by ChEMBL					Assay Description Inhibition of recombinant PDGFR alpha (unknown origin) after 60 mins by z'-lyte kinase assay				Eur J Med Chem 89: 310-9 (2014) Article DOI: 10.1016/j.ejmech.2014.10.044 BindingDB Entry DOI: 10.7270/Q2JQ12NJ
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 1 (Homo sapiens (Human))	BDBM50038423 (CHEMBL3361128) Show SMILES Oc1ccc(\C=C2\Oc3ccccc3C2=O)cc1O Show InChI InChI=1S/C15H10O4/c16-11-6-5-9(7-12(11)17)8-14-15(18)10-3-1-2-4-13(10)19-14/h1-8,16-17H/b14-8+	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
Fudan University Curated by ChEMBL					Assay Description Inhibition of recombinant FLT1 (unknown origin) after 60 mins by z'-lyte kinase assay				Eur J Med Chem 89: 310-9 (2014) Article DOI: 10.1016/j.ejmech.2014.10.044 BindingDB Entry DOI: 10.7270/Q2JQ12NJ
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM50038423 (CHEMBL3361128) Show SMILES Oc1ccc(\C=C2\Oc3ccccc3C2=O)cc1O Show InChI InChI=1S/C15H10O4/c16-11-6-5-9(7-12(11)17)8-14-15(18)10-3-1-2-4-13(10)19-14/h1-8,16-17H/b14-8+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.63E+3	n/a	n/a	n/a	n/a	n/a	n/a
Fudan University Curated by ChEMBL					Assay Description Inhibition of recombinant GSK-3 beta (unknown origin) after 60 mins by z'-lyte kinase assay				Eur J Med Chem 89: 310-9 (2014) Article DOI: 10.1016/j.ejmech.2014.10.044 BindingDB Entry DOI: 10.7270/Q2JQ12NJ
					More data for this Ligand-Target Pair
Aurora kinase A (Homo sapiens (Human))	BDBM50038423 (CHEMBL3361128) Show SMILES Oc1ccc(\C=C2\Oc3ccccc3C2=O)cc1O Show InChI InChI=1S/C15H10O4/c16-11-6-5-9(7-12(11)17)8-14-15(18)10-3-1-2-4-13(10)19-14/h1-8,16-17H/b14-8+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.34E+3	n/a	n/a	n/a	n/a	n/a	n/a
Fudan University Curated by ChEMBL					Assay Description Inhibition of recombinant AURKA (unknown origin) after 60 mins by z'-lyte kinase assay				Eur J Med Chem 89: 310-9 (2014) Article DOI: 10.1016/j.ejmech.2014.10.044 BindingDB Entry DOI: 10.7270/Q2JQ12NJ
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase PLK1 (Homo sapiens (Human))	BDBM50038423 (CHEMBL3361128) Show SMILES Oc1ccc(\C=C2\Oc3ccccc3C2=O)cc1O Show InChI InChI=1S/C15H10O4/c16-11-6-5-9(7-12(11)17)8-14-15(18)10-3-1-2-4-13(10)19-14/h1-8,16-17H/b14-8+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Fudan University Curated by ChEMBL					Assay Description Inhibition of recombinant PLK1 (unknown origin) after 60 mins by z'-lyte kinase assay				Eur J Med Chem 89: 310-9 (2014) Article DOI: 10.1016/j.ejmech.2014.10.044 BindingDB Entry DOI: 10.7270/Q2JQ12NJ
					More data for this Ligand-Target Pair