BDBM50038609 CHEMBL3354866
SMILES: Oc1c(cc2ccccc2c1[S+]([O-])c1ccc(Cl)c(Cl)c1)-c1cccnc1
InChI Key: InChIKey=RETMFBLVLUQPQI-UHFFFAOYSA-N
Data: 2 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Cytochrome P450 11B1, mitochondrial (Homo sapiens (Human)) | BDBM50038609 (CHEMBL3354866) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 8.33E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Saarland University and Helmholtz Institute for Pharmaceutical Research Saarland (HIPS) Curated by ChEMBL | Assay Description Inhibition of human CYP11B1 expressed in hamster V79MZ cells using [3H]-11-deoxycorticosterone as substrate after 1 hr by HPLC analysis | Eur J Med Chem 89: 597-605 (2014) Article DOI: 10.1016/j.ejmech.2014.10.027 BindingDB Entry DOI: 10.7270/Q2X068N3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytochrome P450 11B2 (CYP11B2) (Homo sapiens (Human)) | BDBM50038609 (CHEMBL3354866) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 33 | n/a | n/a | n/a | n/a | n/a | n/a |
Saarland University and Helmholtz Institute for Pharmaceutical Research Saarland (HIPS) Curated by ChEMBL | Assay Description Inhibition of human CYP11B2 expressed in hamster V79MZ cells using [3H]-11-deoxycorticosterone as substrate after 1 hr by HPLC analysis | Eur J Med Chem 89: 597-605 (2014) Article DOI: 10.1016/j.ejmech.2014.10.027 BindingDB Entry DOI: 10.7270/Q2X068N3 | |||||||||||
More data for this Ligand-Target Pair |