BDBM50038729 CHEMBL3354920

SMILES: COc1ccccc1C(=O)N[C@H](COc1cccc(\C=C\C(=O)NO)c1)Cc1c[nH]c2ccccc12

InChI Key:

Data: 8 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50038729   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histone deacetylase (Homo sapiens (Human))	BDBM50038729 (CHEMBL3354920) Show SMILES COc1ccccc1C(=O)N[C@H](COc1cccc(\C=C\C(=O)NO)c1)Cc1c[nH]c2ccccc12 |r| Show InChI	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	39	n/a	n/a	n/a	n/a	n/a	n/a
Shandong University Curated by ChEMBL					Assay Description Inhibition of HDAC in human HeLa cell extract using Boc-Lys (acetyl)-AMC as substrate incubated for 10 mins prior to substrate addition measured afte...				Eur J Med Chem 89: 628-37 (2014) Article DOI: 10.1016/j.ejmech.2014.10.077 BindingDB Entry DOI: 10.7270/Q2NG4S8Z
					More data for this Ligand-Target Pair
Histone deacetylase 11 (Homo sapiens (Human))	BDBM50038729 (CHEMBL3354920) Show SMILES COc1ccccc1C(=O)N[C@H](COc1cccc(\C=C\C(=O)NO)c1)Cc1c[nH]c2ccccc12 |r| Show InChI	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	53	n/a	n/a	n/a	n/a	n/a	n/a
Shandong University Curated by ChEMBL					Assay Description Inhibition of HDAC11 (unknown origin)				Eur J Med Chem 89: 628-37 (2014) Article DOI: 10.1016/j.ejmech.2014.10.077 BindingDB Entry DOI: 10.7270/Q2NG4S8Z
					More data for this Ligand-Target Pair
Histone deacetylase 4 (Homo sapiens (Human))	BDBM50038729 (CHEMBL3354920) Show SMILES COc1ccccc1C(=O)N[C@H](COc1cccc(\C=C\C(=O)NO)c1)Cc1c[nH]c2ccccc12 |r| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	440	n/a	n/a	n/a	n/a	n/a	n/a
Shandong University Curated by ChEMBL					Assay Description Inhibition of HDAC4 (unknown origin)				Eur J Med Chem 89: 628-37 (2014) Article DOI: 10.1016/j.ejmech.2014.10.077 BindingDB Entry DOI: 10.7270/Q2NG4S8Z
					More data for this Ligand-Target Pair
Histone deacetylase 1 (Homo sapiens (Human))	BDBM50038729 (CHEMBL3354920) Show SMILES COc1ccccc1C(=O)N[C@H](COc1cccc(\C=C\C(=O)NO)c1)Cc1c[nH]c2ccccc12 |r| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	33	n/a	n/a	n/a	n/a	n/a	n/a
Shandong University Curated by ChEMBL					Assay Description Inhibition of HDAC1 (unknown origin)				Eur J Med Chem 89: 628-37 (2014) Article DOI: 10.1016/j.ejmech.2014.10.077 BindingDB Entry DOI: 10.7270/Q2NG4S8Z
					More data for this Ligand-Target Pair
Cereblon/Histone deacetylase 6 (Homo sapiens (Human))	BDBM50038729 (CHEMBL3354920) Show SMILES COc1ccccc1C(=O)N[C@H](COc1cccc(\C=C\C(=O)NO)c1)Cc1c[nH]c2ccccc12 |r| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	24	n/a	n/a	n/a	n/a	n/a	n/a
Shandong University Curated by ChEMBL					Assay Description Inhibition of HDAC6 (unknown origin)				Eur J Med Chem 89: 628-37 (2014) Article DOI: 10.1016/j.ejmech.2014.10.077 BindingDB Entry DOI: 10.7270/Q2NG4S8Z
					More data for this Ligand-Target Pair
Histone deacetylase 3 (Homo sapiens (Human))	BDBM50038729 (CHEMBL3354920) Show SMILES COc1ccccc1C(=O)N[C@H](COc1cccc(\C=C\C(=O)NO)c1)Cc1c[nH]c2ccccc12 |r| Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	29	n/a	n/a	n/a	n/a	n/a	n/a
Shandong University Curated by ChEMBL					Assay Description Inhibition of HDAC3 (unknown origin)				Eur J Med Chem 89: 628-37 (2014) Article DOI: 10.1016/j.ejmech.2014.10.077 BindingDB Entry DOI: 10.7270/Q2NG4S8Z
					More data for this Ligand-Target Pair
Histone deacetylase 2 (Homo sapiens (Human))	BDBM50038729 (CHEMBL3354920) Show SMILES COc1ccccc1C(=O)N[C@H](COc1cccc(\C=C\C(=O)NO)c1)Cc1c[nH]c2ccccc12 |r| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	65	n/a	n/a	n/a	n/a	n/a	n/a
Shandong University Curated by ChEMBL					Assay Description Inhibition of HDAC2 (unknown origin)				Eur J Med Chem 89: 628-37 (2014) Article DOI: 10.1016/j.ejmech.2014.10.077 BindingDB Entry DOI: 10.7270/Q2NG4S8Z
					More data for this Ligand-Target Pair
Histone deacetylase 8 (Homo sapiens (Human))	BDBM50038729 (CHEMBL3354920) Show SMILES COc1ccccc1C(=O)N[C@H](COc1cccc(\C=C\C(=O)NO)c1)Cc1c[nH]c2ccccc12 |r| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	87	n/a	n/a	n/a	n/a	n/a	n/a
Shandong University Curated by ChEMBL					Assay Description Inhibition of HDAC8 (unknown origin)				Eur J Med Chem 89: 628-37 (2014) Article DOI: 10.1016/j.ejmech.2014.10.077 BindingDB Entry DOI: 10.7270/Q2NG4S8Z
					More data for this Ligand-Target Pair