BDBM50038752 CHEMBL64636::[6-(4-Fluoro-phenoxy)-1H-indol-3-yl]-((R)-2-pyridin-3-yl-thiazolidin-4-yl)-methanone

SMILES: Fc1ccc(Oc2ccc3c(c[nH]c3c2)C(=O)[C@@H]2CSC(N2)c2cccnc2)cc1

InChI Key: InChIKey=BTORIACRBGWOOJ-BBQAJUCSSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50038752   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Platelet activating factor receptor (Cavia porcellus)	BDBM50038752 (CHEMBL64636 | [6-(4-Fluoro-phenoxy)-1H-indol-3-yl]...) Show SMILES Fc1ccc(Oc2ccc3c(c[nH]c3c2)C(=O)[C@@H]2CSC(N2)c2cccnc2)cc1 Show InChI InChI=1S/C23H18FN3O2S/c24-15-3-5-16(6-4-15)29-17-7-8-18-19(12-26-20(18)10-17)22(28)21-13-30-23(27-21)14-2-1-9-25-11-14/h1-12,21,23,26-27H,13H2/t21-,23?/m0/s1	MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Antagonist activity against platelet activating factor (PAF) receptor in rabbit platelet membranes using [3H]C18-PAF as radioligand				J Med Chem 37: 2011-32 (1994) BindingDB Entry DOI: 10.7270/Q2GH9JM7
					More data for this Ligand-Target Pair