BDBM50038798 2,5-Dimethyl-3-(2-pyridin-3-yl-thiazolidine-4-carbonyl)-indole-1-carboxylic acid dimethylamide::CHEMBL292508

SMILES: CN(C)C(=O)n1c(C)c(C(=O)[C@@H]2CSC(N2)c2cccnc2)c2cc(C)ccc12

InChI Key: InChIKey=DRTJMPXMIBMRRV-PBVYKCSPSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50038798   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Platelet activating factor receptor (Cavia porcellus)	BDBM50038798 (2,5-Dimethyl-3-(2-pyridin-3-yl-thiazolidine-4-carb...) Show SMILES CN(C)C(=O)n1c(C)c(C(=O)[C@@H]2CSC(N2)c2cccnc2)c2cc(C)ccc12 Show InChI InChI=1S/C22H24N4O2S/c1-13-7-8-18-16(10-13)19(14(2)26(18)22(28)25(3)4)20(27)17-12-29-21(24-17)15-6-5-9-23-11-15/h5-11,17,21,24H,12H2,1-4H3/t17-,21?/m0/s1	MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	13	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Antagonist activity against platelet activating factor (PAF) receptor in rabbit platelet membranes using [3H]C18-PAF as radioligand				J Med Chem 37: 2011-32 (1994) BindingDB Entry DOI: 10.7270/Q2GH9JM7
					More data for this Ligand-Target Pair