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BDBM50038818 2-Methyl-3-((R)-2-pyridin-3-yl-thiazolidine-4-carbonyl)-indole-1-carboxylic acid tert-butyl ester; compound with oxalic acid::CHEMBL64882

SMILES: Cc1c(C(=O)[C@@H]2CSC(N2)c2cccnc2)c2ccccc2n1C(=O)OC(C)(C)C

InChI Key: InChIKey=MFNYEEHXLOMCLT-PBVYKCSPSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50038818   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Platelet activating factor receptor


(Cavia porcellus)
BDBM50038818
PNG
(2-Methyl-3-((R)-2-pyridin-3-yl-thiazolidine-4-carb...)
Show SMILES Cc1c(C(=O)[C@@H]2CSC(N2)c2cccnc2)c2ccccc2n1C(=O)OC(C)(C)C
Show InChI InChI=1S/C23H25N3O3S/c1-14-19(20(27)17-13-30-21(25-17)15-8-7-11-24-12-15)16-9-5-6-10-18(16)26(14)22(28)29-23(2,3)4/h5-12,17,21,25H,13H2,1-4H3/t17-,21?/m0/s1
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PC cid
PC sid
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9.5n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Antagonist activity against platelet activating factor (PAF) receptor in rabbit platelet membranes using [3H]C18-PAF as radioligand


J Med Chem 37: 2011-32 (1994)


BindingDB Entry DOI: 10.7270/Q2GH9JM7
More data for this
Ligand-Target Pair