BDBM50038974 CHEMBL68337::{4-[(Benzo[1,3]dioxol-5-ylmethyl)-amino]-quinazolin-6-yl}-methanol

SMILES: OCc1ccc2ncnc(NCc3ccc4OCOc4c3)c2c1

InChI Key: InChIKey=KHEDDQOJHSWVHB-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50038974   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cGMP-specific 3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM50038974 (CHEMBL68337 | {4-[(Benzo[1,3]dioxol-5-ylmethyl)-am...) Show SMILES OCc1ccc2ncnc(NCc3ccc4OCOc4c3)c2c1 Show InChI InChI=1S/C17H15N3O3/c21-8-12-1-3-14-13(5-12)17(20-9-19-14)18-7-11-2-4-15-16(6-11)23-10-22-15/h1-6,9,21H,7-8,10H2,(H,18,19,20)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	930	n/a	n/a	n/a	n/a	n/a	n/a
Eisai Company Ltd. Curated by ChEMBL					Assay Description Inhibitory activity against cGMP-phosphodiesterase from porcine aorta				J Med Chem 37: 2106-11 (1994) BindingDB Entry DOI: 10.7270/Q2Q52NPF
					More data for this Ligand-Target Pair