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SMILES: COc1ccc(cn1)-c1cnc2cc(OC)c(OC)cc2c1

InChI Key: InChIKey=NXAGIDNAFCDRSJ-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50039062   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Platelet-derived growth factor receptor alpha/beta (Homo sapiens (Human))	BDBM50039062 (6,7-Dimethoxy-3-(6-methoxy-pyridin-3-yl)-quinoline...) Show SMILES COc1ccc(cn1)-c1cnc2cc(OC)c(OC)cc2c1 Show InChI InChI=1S/C17H16N2O3/c1-20-15-7-12-6-13(10-18-14(12)8-16(15)21-2)11-4-5-17(22-3)19-9-11/h4-10H,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	70	n/a	n/a	n/a	n/a	n/a	n/a
Rhône-Poulenc Rorer Central Research Curated by ChEMBL					Assay Description Inhibition of human PDGF receptor phosphorylation; 0.008-0.07				J Med Chem 37: 2129-37 (1994) BindingDB Entry DOI: 10.7270/Q29Z93Z8
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50039062 (6,7-Dimethoxy-3-(6-methoxy-pyridin-3-yl)-quinoline...) Show SMILES COc1ccc(cn1)-c1cnc2cc(OC)c(OC)cc2c1 Show InChI InChI=1S/C17H16N2O3/c1-20-15-7-12-6-13(10-18-14(12)8-16(15)21-2)11-4-5-17(22-3)19-9-11/h4-10H,1-3H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Rhône-Poulenc Rorer Central Research Curated by ChEMBL					Assay Description Concentration required to inhibit phosphorylation of isolated human epidermal growth factor tyrosine kinase receptor by 50%				J Med Chem 37: 2129-37 (1994) BindingDB Entry DOI: 10.7270/Q29Z93Z8
					More data for this Ligand-Target Pair