BDBM50039084 3-(3-Fluoro-phenyl)-6,7-dimethoxy-quinoline::CHEMBL302491

SMILES: COc1cc2cc(cnc2cc1OC)-c1cccc(F)c1

InChI Key: InChIKey=UECRIUGPTSAZMC-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50039084   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50039084 (3-(3-Fluoro-phenyl)-6,7-dimethoxy-quinoline | CHEM...) Show SMILES COc1cc2cc(cnc2cc1OC)-c1cccc(F)c1 Show InChI InChI=1S/C17H14FNO2/c1-20-16-8-12-6-13(11-4-3-5-14(18)7-11)10-19-15(12)9-17(16)21-2/h3-10H,1-2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Rhône-Poulenc Rorer Central Research Curated by ChEMBL					Assay Description Concentration required to inhibit phosphorylation of isolated human epidermal growth factor tyrosine kinase receptor by 50%				J Med Chem 37: 2129-37 (1994) BindingDB Entry DOI: 10.7270/Q29Z93Z8
					More data for this Ligand-Target Pair
PDGFR-beta/Platelet-derived growth factor receptor alpha (Homo sapiens (Human))	BDBM50039084 (3-(3-Fluoro-phenyl)-6,7-dimethoxy-quinoline | CHEM...) Show SMILES COc1cc2cc(cnc2cc1OC)-c1cccc(F)c1 Show InChI InChI=1S/C17H14FNO2/c1-20-16-8-12-6-13(11-4-3-5-14(18)7-11)10-19-15(12)9-17(16)21-2/h3-10H,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	25	n/a	n/a	n/a	n/a	n/a	n/a
Rhône-Poulenc Rorer Central Research Curated by ChEMBL					Assay Description Inhibition of human PDGF receptor phosphorylation; 0.015-0.025				J Med Chem 37: 2129-37 (1994) BindingDB Entry DOI: 10.7270/Q29Z93Z8
					More data for this Ligand-Target Pair