null
SMILES: Oc1cc(O)c2cc(cnc2c1)-c1ccncc1
InChI Key: InChIKey=QYWQBBCHWNMFSG-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Platelet-derived growth factor receptor alpha/beta (Homo sapiens (Human)) | BDBM50039652 (3-Pyridin-4-yl-quinoline-5,7-diol | CHEMBL87083) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 1.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Sterling Winthrop Pharmaceuticals Research Division Curated by ChEMBL | Assay Description Inhibition of Platelet-derived growth factor receptor tyrosine kinase | J Med Chem 37: 2627-9 (1994) BindingDB Entry DOI: 10.7270/Q2CR5SDD | |||||||||||
More data for this Ligand-Target Pair |