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SMILES: OC(=O)c1ccc2OCc3ccccc3C(SCCN3CCN(CC3)c3ccc(F)cc3)c2c1

InChI Key: InChIKey=RDVZRVWKUVTRIW-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50040113   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Histamine H1 receptor


(Cavia porcellus (domestic guinea pig))		BDBM50040113
PNG
(11-{2-[4-(4-Fluoro-phenyl)-piperazin-1-yl]-ethylsu...)
Show SMILES OC(=O)c1ccc2OCc3ccccc3C(SCCN3CCN(CC3)c3ccc(F)cc3)c2c1
Show InChI InChI=1S/C27H27FN2O3S/c28-21-6-8-22(9-7-21)30-13-11-29(12-14-30)15-16-34-26-23-4-2-1-3-20(23)18-33-25-10-5-19(27(31)32)17-24(25)26/h1-10,17,26H,11-16,18H2,(H,31,32)
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PubMed
 41n/an/an/an/an/an/an/an/a



Kyowa Hakko Kogyo Co.

Curated by ChEMBL


Assay Description
Inhibition of the specific binding of [3H]-pyrilamine to guinea pig cerebellum histamine H1 receptor

J Med Chem 36: 417-20 (1993)


BindingDB Entry DOI: 10.7270/Q2Q23Z9K
More data for this
Ligand-Target Pair