BDBM50040190 1-Benzo[b]thiophen-2-yl-cyclohexylamine::CHEMBL18556
SMILES: NC1(CCCCC1)c1cc2ccccc2s1
InChI Key: InChIKey=HYVMNAZTYJDWIZ-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human)) | BDBM50040190 (1-Benzo[b]thiophen-2-yl-cyclohexylamine | CHEMBL18...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | 3.17E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL | Assay Description Inhibition of [3H](+)-pentazocine binding to sigma receptor of guinea pig brain homogenates | J Med Chem 36: 1188-93 (1993) BindingDB Entry DOI: 10.7270/Q23F4Q98 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent dopamine transporter (Rattus norvegicus (rat)) | BDBM50040190 (1-Benzo[b]thiophen-2-yl-cyclohexylamine | CHEMBL18...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 684 | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL | Assay Description Inhibition of [3H]cocaine binding to rat forebrain dopamine receptor | J Med Chem 36: 1188-93 (1993) BindingDB Entry DOI: 10.7270/Q23F4Q98 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent dopamine transporter (Rattus norvegicus (rat)) | BDBM50040190 (1-Benzo[b]thiophen-2-yl-cyclohexylamine | CHEMBL18...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 123 | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL | Assay Description Displacement of [3H]BTCP (1-[1-(2-benxo[b]thienyl)cyclohexyl]piperidine) from rat forebrain dopamine transporter | J Med Chem 36: 1188-93 (1993) BindingDB Entry DOI: 10.7270/Q23F4Q98 | |||||||||||
More data for this Ligand-Target Pair |