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BDBM50040324 CHEMBL266516::PhCH2CH2(CO)His-(BzthAla)-Ala-Val-DAla-His-Pro(psi)-Phe-NH2

SMILES: CC(C)[C@H](NC(=O)[C@H](C)NC(=O)[C@H](Cc1csc2ccccc12)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CCc1ccccc1)C(=O)N[C@@H](C)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@@H]1CN[C@@H](Cc1ccccc1)C(N)=O

InChI Key: InChIKey=SEBSJLNQDQWMLK-ARGXZMAYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50040324   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Gastrin releasing peptide receptor


(MOUSE)		BDBM50040324
PNG
(CHEMBL266516 | PhCH2CH2(CO)His-(BzthAla)-Ala-Val-D...)
Show SMILES CC(C)[C@H](NC(=O)[C@H](C)NC(=O)[C@H](Cc1csc2ccccc12)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CCc1ccccc1)C(=O)N[C@@H](C)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@@H]1CN[C@@H](Cc1ccccc1)C(N)=O
Show InChI InChI=1S/C57H71N13O8S/c1-34(2)50(56(77)65-35(3)52(73)68-47(27-41-29-60-33-63-41)57(78)70-23-13-18-42(70)30-61-44(51(58)72)24-38-16-9-6-10-17-38)69-53(74)36(4)64-54(75)45(25-39-31-79-48-20-12-11-19-43(39)48)67-55(76)46(26-40-28-59-32-62-40)66-49(71)22-21-37-14-7-5-8-15-37/h5-12,14-17,19-20,28-29,31-36,42,44-47,50,61H,13,18,21-27,30H2,1-4H3,(H2,58,72)(H,59,62)(H,60,63)(H,64,75)(H,65,77)(H,66,71)(H,67,76)(H,68,73)(H,69,74)/t35-,36-,42+,44-,45-,46-,47-,50-/m0/s1
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Similars
PubMed
n/an/a 0.75n/an/an/an/an/an/a



Burroughs Wellcome Company

Curated by ChEMBL


Assay Description
Ability of peptide to inhibit binding of 10 pM [125I]-gastrin releasing peptide to S-3T3 cell membrane.

J Med Chem 37: 439-45 (1994)


BindingDB Entry DOI: 10.7270/Q2ST7NXN
More data for this
Ligand-Target Pair