BDBM50040373 CHEMBL344720::N-(1,3-Bis-cyclopropylmethyl-7-methyl-2,6-dioxo-2,3,6,7-tetrahydro-1H-purin-8-yl)-benzenesulfonamide

SMILES: Cn1c(NS(=O)(=O)c2ccccc2)nc2n(CC3CC3)c(=O)n(CC3CC3)c(=O)c12

InChI Key: InChIKey=XGQMAYDPDYXFKL-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50040373   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cGMP-specific 3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM50040373 (CHEMBL344720 | N-(1,3-Bis-cyclopropylmethyl-7-meth...) Show SMILES Cn1c(NS(=O)(=O)c2ccccc2)nc2n(CC3CC3)c(=O)n(CC3CC3)c(=O)c12 Show InChI InChI=1S/C20H23N5O4S/c1-23-16-17(21-19(23)22-30(28,29)15-5-3-2-4-6-15)24(11-13-7-8-13)20(27)25(18(16)26)12-14-9-10-14/h2-6,13-14H,7-12H2,1H3,(H,21,22)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	5.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham Pharmaceuticals Curated by ChEMBL					Assay Description Concentration required to inhibit 50% activity of phosphodiesterase VA isoenzyme at 100 microM.				J Med Chem 37: 476-85 (1994) BindingDB Entry DOI: 10.7270/Q2P26X6N
					More data for this Ligand-Target Pair