BDBM50040409 (S)-2-[3-Biphenyl-4-yl-2-(phosphonomethyl-amino)-propionylamino]-propionic acid::CHEMBL146594

SMILES: C[C@H](NC(=O)C(Cc1ccc(cc1)-c1ccccc1)NCP(O)(O)=O)C(O)=O

InChI Key: InChIKey=FPJWKLATJZBTIV-CWQZNGJJSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50040409   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Neprilysin (Rattus norvegicus (Rat))	BDBM50040409 ((S)-2-[3-Biphenyl-4-yl-2-(phosphonomethyl-amino)-p...) Show SMILES C[C@H](NC(=O)C(Cc1ccc(cc1)-c1ccccc1)NCP(O)(O)=O)C(O)=O Show InChI InChI=1S/C19H23N2O6P/c1-13(19(23)24)21-18(22)17(20-12-28(25,26)27)11-14-7-9-16(10-8-14)15-5-3-2-4-6-15/h2-10,13,17,20H,11-12H2,1H3,(H,21,22)(H,23,24)(H2,25,26,27)/t13-,17?/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
CIBA-GEIGY Corporation Curated by ChEMBL					Assay Description In vitro inhibition of Neutral endopeptidase (NEP) enzyme				J Med Chem 37: 498-511 (1994) BindingDB Entry DOI: 10.7270/Q2H70GF9
					More data for this Ligand-Target Pair