BDBM50040411 CHEMBL357903::[3-Biphenyl-4-yl-2-(phosphonomethyl-amino)-propionylamino]-acetic acid

SMILES: OC(=O)CNC(=O)C(Cc1ccc(cc1)-c1ccccc1)NCP(O)(O)=O

InChI Key: InChIKey=RCGSYJNOCWJPHN-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50040411   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Neutral Endopeptidase (NEP) (Rattus norvegicus (Rat))	BDBM50040411 (CHEMBL357903 | [3-Biphenyl-4-yl-2-(phosphonomethyl...) Show SMILES OC(=O)CNC(=O)C(Cc1ccc(cc1)-c1ccccc1)NCP(O)(O)=O Show InChI InChI=1S/C18H21N2O6P/c21-17(22)11-19-18(23)16(20-12-27(24,25)26)10-13-6-8-15(9-7-13)14-4-2-1-3-5-14/h1-9,16,20H,10-12H2,(H,19,23)(H,21,22)(H2,24,25,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
CIBA-GEIGY Corporation Curated by ChEMBL					Assay Description In vitro inhibition of Neutral endopeptidase (NEP) enzyme				J Med Chem 37: 498-511 (1994) BindingDB Entry DOI: 10.7270/Q2H70GF9
					More data for this Ligand-Target Pair