BDBM50040413 (S)-2-{(S)-2-[Hydroxy-(3,4,5-trihydroxy-6-methyl-tetrahydro-pyran-2-yloxy)-phosphorylamino]-4-methyl-pentanoylamino}-3-(1H-indol-3-yl)-propionic acid anion::CHEMBL418012
SMILES: CC(C)C[C@H](NP(O)(=O)OC1OC(C)C(O)C(O)C1O)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O
InChI Key: InChIKey=ZPHBZEQOLSRPAK-ASWWRILVSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Endothelin-converting enzyme 1 (ECE) (Rattus norvegicus (Rat)) | BDBM50040413 ((S)-2-{(S)-2-[Hydroxy-(3,4,5-trihydroxy-6-methyl-t...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 690 | n/a | n/a | n/a | n/a | n/a | n/a |
Sumitomo Pharmaceuticals Co., Ltd. Curated by ChEMBL | Assay Description Tested in vitro for inhibition of Endothelin-converting enzyme (ECE) of rat lung membrane | Bioorg Med Chem Lett 12: 1275-8 (2002) BindingDB Entry DOI: 10.7270/Q2R49RBT | |||||||||||
More data for this Ligand-Target Pair |