BDBM50040431 CHEMBL3360602

SMILES: COc1cc2c(Nc3ccc(F)c(Cl)c3)ncnc2cc1OCCCn1ccnc1[N+]([O-])=O

InChI Key: InChIKey=LHRIOONCESTBQE-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50040431   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50040431 (CHEMBL3360602) Show SMILES COc1cc2c(Nc3ccc(F)c(Cl)c3)ncnc2cc1OCCCn1ccnc1[N+]([O-])=O Show InChI InChI=1S/C21H18ClFN6O4/c1-32-18-10-14-17(25-12-26-20(14)27-13-3-4-16(23)15(22)9-13)11-19(18)33-8-2-6-28-7-5-24-21(28)29(30)31/h3-5,7,9-12H,2,6,8H2,1H3,(H,25,26,27)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.770	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of wild type EGFR (unknown origin) by Z'-Lyte kinase assay				Bioorg Med Chem 22: 6796-805 (2015) Article DOI: 10.1016/j.bmc.2014.10.038 BindingDB Entry DOI: 10.7270/Q22J6DHQ
					More data for this Ligand-Target Pair