null

SMILES: CNC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(C)C)N[C@H](CCN1C(=O)c2cc3ccccc3cc2C1=O)C(O)=O

InChI Key: InChIKey=LGAMBGLWTORDNW-ZRBLBEILSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50040580   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Matrix metalloproteinase-9 (Homo sapiens (Human))	BDBM50040580 ((R)-4-(1,3-Dioxo-1,3-dihydro-benzo[f]isoindol-2-yl...) Show SMILES CNC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(C)C)N[C@H](CCN1C(=O)c2cc3ccccc3cc2C1=O)C(O)=O Show InChI InChI=1S/C29H39N7O6/c1-16(2)13-23(25(38)35-21(24(37)32-3)9-6-11-33-29(30)31)34-22(28(41)42)10-12-36-26(39)19-14-17-7-4-5-8-18(17)15-20(19)27(36)40/h4-5,7-8,14-16,21-23,34H,6,9-13H2,1-3H3,(H,32,37)(H,35,38)(H,41,42)(H4,30,31,33)/t21-,22+,23-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	27	n/a	n/a	n/a	n/a	n/a	n/a
Glaxo Incorporated Research Institute Curated by ChEMBL					Assay Description Activity against human gelatinase (MMP-9).				J Med Chem 37: 674-88 (1994) BindingDB Entry DOI: 10.7270/Q2RV0MRC
					More data for this Ligand-Target Pair
Stromelysin-1 (Homo sapiens (Human))	BDBM50040580 ((R)-4-(1,3-Dioxo-1,3-dihydro-benzo[f]isoindol-2-yl...) Show SMILES CNC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(C)C)N[C@H](CCN1C(=O)c2cc3ccccc3cc2C1=O)C(O)=O Show InChI InChI=1S/C29H39N7O6/c1-16(2)13-23(25(38)35-21(24(37)32-3)9-6-11-33-29(30)31)34-22(28(41)42)10-12-36-26(39)19-14-17-7-4-5-8-18(17)15-20(19)27(36)40/h4-5,7-8,14-16,21-23,34H,6,9-13H2,1-3H3,(H,32,37)(H,35,38)(H,41,42)(H4,30,31,33)/t21-,22+,23-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	481	n/a	n/a	n/a	n/a	n/a	n/a
Glaxo Incorporated Research Institute Curated by ChEMBL					Assay Description Activity against human stromelysin (MMP-3).				J Med Chem 37: 674-88 (1994) BindingDB Entry DOI: 10.7270/Q2RV0MRC
					More data for this Ligand-Target Pair
Interstitial collagenase (Homo sapiens (Human))	BDBM50040580 ((R)-4-(1,3-Dioxo-1,3-dihydro-benzo[f]isoindol-2-yl...) Show SMILES CNC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(C)C)N[C@H](CCN1C(=O)c2cc3ccccc3cc2C1=O)C(O)=O Show InChI InChI=1S/C29H39N7O6/c1-16(2)13-23(25(38)35-21(24(37)32-3)9-6-11-33-29(30)31)34-22(28(41)42)10-12-36-26(39)19-14-17-7-4-5-8-18(17)15-20(19)27(36)40/h4-5,7-8,14-16,21-23,34H,6,9-13H2,1-3H3,(H,32,37)(H,35,38)(H,41,42)(H4,30,31,33)/t21-,22+,23-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	152	n/a	n/a	n/a	n/a	n/a	n/a
Glaxo Incorporated Research Institute Curated by ChEMBL					Assay Description Activity against human collagenase (MMP-1).				J Med Chem 37: 674-88 (1994) BindingDB Entry DOI: 10.7270/Q2RV0MRC
					More data for this Ligand-Target Pair