null

SMILES: CCCOc1ccc2C(=O)N(CC[C@@H](N[C@@H](CC(C)C)C(=O)N[C@@H](Cc3ccccc3)C(=O)NC)C(O)=O)C(=O)c2c1

InChI Key: InChIKey=FRRDNYNCIZOSSI-ZNZIZOMTSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50040583   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Matrix metalloproteinase-9 (Homo sapiens (Human))	BDBM50040583 ((R)-4-(1,3-Dioxo-5-propoxy-1,3-dihydro-isoindol-2-...) Show SMILES CCCOc1ccc2C(=O)N(CC[C@@H](N[C@@H](CC(C)C)C(=O)N[C@@H](Cc3ccccc3)C(=O)NC)C(O)=O)C(=O)c2c1 Show InChI InChI=1S/C31H40N4O7/c1-5-15-42-21-11-12-22-23(18-21)30(39)35(29(22)38)14-13-24(31(40)41)33-25(16-19(2)3)28(37)34-26(27(36)32-4)17-20-9-7-6-8-10-20/h6-12,18-19,24-26,33H,5,13-17H2,1-4H3,(H,32,36)(H,34,37)(H,40,41)/t24-,25+,26+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.10	n/a	n/a	n/a	n/a	n/a	n/a
Glaxo Incorporated Research Institute Curated by ChEMBL					Assay Description Activity against human gelatinase (MMP-9).				J Med Chem 37: 674-88 (1994) BindingDB Entry DOI: 10.7270/Q2RV0MRC
					More data for this Ligand-Target Pair
Stromelysin-1 (Homo sapiens (Human))	BDBM50040583 ((R)-4-(1,3-Dioxo-5-propoxy-1,3-dihydro-isoindol-2-...) Show SMILES CCCOc1ccc2C(=O)N(CC[C@@H](N[C@@H](CC(C)C)C(=O)N[C@@H](Cc3ccccc3)C(=O)NC)C(O)=O)C(=O)c2c1 Show InChI InChI=1S/C31H40N4O7/c1-5-15-42-21-11-12-22-23(18-21)30(39)35(29(22)38)14-13-24(31(40)41)33-25(16-19(2)3)28(37)34-26(27(36)32-4)17-20-9-7-6-8-10-20/h6-12,18-19,24-26,33H,5,13-17H2,1-4H3,(H,32,36)(H,34,37)(H,40,41)/t24-,25+,26+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	427	n/a	n/a	n/a	n/a	n/a	n/a
Glaxo Incorporated Research Institute Curated by ChEMBL					Assay Description Activity against human stromelysin (MMP-3).				J Med Chem 37: 674-88 (1994) BindingDB Entry DOI: 10.7270/Q2RV0MRC
					More data for this Ligand-Target Pair
Interstitial collagenase (Homo sapiens (Human))	BDBM50040583 ((R)-4-(1,3-Dioxo-5-propoxy-1,3-dihydro-isoindol-2-...) Show SMILES CCCOc1ccc2C(=O)N(CC[C@@H](N[C@@H](CC(C)C)C(=O)N[C@@H](Cc3ccccc3)C(=O)NC)C(O)=O)C(=O)c2c1 Show InChI InChI=1S/C31H40N4O7/c1-5-15-42-21-11-12-22-23(18-21)30(39)35(29(22)38)14-13-24(31(40)41)33-25(16-19(2)3)28(37)34-26(27(36)32-4)17-20-9-7-6-8-10-20/h6-12,18-19,24-26,33H,5,13-17H2,1-4H3,(H,32,36)(H,34,37)(H,40,41)/t24-,25+,26+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
Glaxo Incorporated Research Institute Curated by ChEMBL					Assay Description Activity against human collagenase (MMP-1).				J Med Chem 37: 674-88 (1994) BindingDB Entry DOI: 10.7270/Q2RV0MRC
					More data for this Ligand-Target Pair