BDBM50041107 6-(4-Phenoxy-phenyl)-5H-[1,3]dioxolo[4,5-g]quinolin-8-one::CHEMBL14544

SMILES: Oc1cc(nc2cc3OCOc3cc12)-c1ccc(Oc2ccccc2)cc1

InChI Key: InChIKey=RLBXEENBVHIEDK-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50041107   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tubulin (Bos taurus)	BDBM50041107 (6-(4-Phenoxy-phenyl)-5H-[1,3]dioxolo[4,5-g]quinoli...) Show SMILES Oc1cc(nc2cc3OCOc3cc12)-c1ccc(Oc2ccccc2)cc1 Show InChI InChI=1S/C22H15NO4/c24-20-11-18(23-19-12-22-21(10-17(19)20)25-13-26-22)14-6-8-16(9-7-14)27-15-4-2-1-3-5-15/h1-12H,13H2,(H,23,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>4.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
School of Pharmacy Curated by ChEMBL					Assay Description Inhibition of tubulin polymerization				J Med Chem 37: 1126-35 (1994) BindingDB Entry DOI: 10.7270/Q2ZC81XN
					More data for this Ligand-Target Pair