BDBM50041119 2-(2-fluorophenyl)-6,7-methylenedioxyquinolin-4-one::6-(2-Fluoro-phenyl)-5H-[1,3]dioxolo[4,5-g]quinolin-8-one::6-(2-fluorophenyl)-[1,3]dioxolo[4,5-g]quinolin-8(5H)-one::CHEMBL280099::NSC-656158

SMILES: Oc1cc(nc2cc3OCOc3cc12)-c1ccccc1F

InChI Key: InChIKey=ZMYDAPJHGNEFGQ-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50041119   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tubulin (Bos taurus)	BDBM50041119 (2-(2-fluorophenyl)-6,7-methylenedioxyquinolin-4-on...) Show SMILES Oc1cc(nc2cc3OCOc3cc12)-c1ccccc1F Show InChI InChI=1S/C16H10FNO3/c17-11-4-2-1-3-9(11)12-6-14(19)10-5-15-16(21-8-20-15)7-13(10)18-12/h1-7H,8H2,(H,18,19)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	850	n/a	n/a	n/a	n/a	n/a	n/a
School of Pharmacy Curated by ChEMBL					Assay Description Inhibition of tubulin polymerization				J Med Chem 37: 1126-35 (1994) BindingDB Entry DOI: 10.7270/Q2ZC81XN
					More data for this Ligand-Target Pair
Tubulin (Sus scrofa (Pig))	BDBM50041119 (2-(2-fluorophenyl)-6,7-methylenedioxyquinolin-4-on...) Show SMILES Oc1cc(nc2cc3OCOc3cc12)-c1ccccc1F Show InChI InChI=1S/C16H10FNO3/c17-11-4-2-1-3-9(11)12-6-14(19)10-5-15-16(21-8-20-15)7-13(10)18-12/h1-7H,8H2,(H,18,19)	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	3.90E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of North Carolina Curated by ChEMBL					Assay Description Percent inhibition of colchicine binding(ICB) at 5 uM [3H]-colchicine concentration				J Med Chem 44: 3932-6 (2001) BindingDB Entry DOI: 10.7270/Q2PK0FFW
					More data for this Ligand-Target Pair
Tubulin (Sus scrofa (Pig))	BDBM50041119 (2-(2-fluorophenyl)-6,7-methylenedioxyquinolin-4-on...) Show SMILES Oc1cc(nc2cc3OCOc3cc12)-c1ccccc1F Show InChI InChI=1S/C16H10FNO3/c17-11-4-2-1-3-9(11)12-6-14(19)10-5-15-16(21-8-20-15)7-13(10)18-12/h1-7H,8H2,(H,18,19)	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	680	n/a	n/a	n/a	n/a	n/a	n/a
University of North Carolina Curated by ChEMBL					Assay Description Inhibition of tubulin polymerization(ITP)				J Med Chem 44: 3932-6 (2001) BindingDB Entry DOI: 10.7270/Q2PK0FFW
					More data for this Ligand-Target Pair