BDBM50041228 3-(6-Carbamimidoyl-naphthalen-2-yl)-2-[4-((S)-pyrrolidin-3-yloxy)-phenyl]-propionic acid ethyl ester::CHEMBL279270

SMILES: CCOC(=O)C(Cc1ccc2cc(ccc2c1)C(N)=N)c1ccc(O[C@H]2CCNC2)cc1

InChI Key: InChIKey=VWENWTAMDZAVEI-UXMRNZNESA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50041228   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Coagulation factor X (Homo sapiens (Human))	BDBM50041228 (3-(6-Carbamimidoyl-naphthalen-2-yl)-2-[4-((S)-pyrr...) Show SMILES CCOC(=O)C(Cc1ccc2cc(ccc2c1)C(N)=N)c1ccc(O[C@H]2CCNC2)cc1 Show InChI InChI=1S/C26H29N3O3/c1-2-31-26(30)24(18-7-9-22(10-8-18)32-23-11-12-29-16-23)14-17-3-4-20-15-21(25(27)28)6-5-19(20)13-17/h3-10,13,15,23-24,29H,2,11-12,14,16H2,1H3,(H3,27,28)/t23-,24?/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	4.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Daiichi Pharmaceutical Company, Ltd. Curated by ChEMBL					Assay Description In vitro evaluation for the concentration needed for inhibiting factor Xa by 50%				J Med Chem 37: 1200-7 (1994) BindingDB Entry DOI: 10.7270/Q2FF3RF6
					More data for this Ligand-Target Pair
Prothrombin (Homo sapiens (Human))	BDBM50041228 (3-(6-Carbamimidoyl-naphthalen-2-yl)-2-[4-((S)-pyrr...) Show SMILES CCOC(=O)C(Cc1ccc2cc(ccc2c1)C(N)=N)c1ccc(O[C@H]2CCNC2)cc1 Show InChI InChI=1S/C26H29N3O3/c1-2-31-26(30)24(18-7-9-22(10-8-18)32-23-11-12-29-16-23)14-17-3-4-20-15-21(25(27)28)6-5-19(20)13-17/h3-10,13,15,23-24,29H,2,11-12,14,16H2,1H3,(H3,27,28)/t23-,24?/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	3.80E+4	n/a	n/a	n/a	n/a	n/a	n/a
Daiichi Pharmaceutical Company, Ltd. Curated by ChEMBL					Assay Description In vitro evaluation for the concentration needed for inhibiting thrombin by 50%				J Med Chem 37: 1200-7 (1994) BindingDB Entry DOI: 10.7270/Q2FF3RF6
					More data for this Ligand-Target Pair