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BDBM50041338 3-[2-Methoxy-4-(toluene-2-sulfonylaminocarbonyl)-benzyl]-1-methyl-1H-indole-5-carboxylic acid (2-trifluoromethyl-hexyl)-amide::CHEMBL286827

SMILES: CCCCC(CNC(=O)c1ccc2n(C)cc(Cc3ccc(cc3OC)C(=O)NS(=O)(=O)c3ccccc3C)c2c1)C(F)(F)F

InChI Key: InChIKey=HKMXHNTXGRDABK-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50041338   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Cysteinyl leukotriene receptor 1


(GUINEA PIG)		BDBM50041338
PNG
(3-[2-Methoxy-4-(toluene-2-sulfonylaminocarbonyl)-b...)
Show SMILES CCCCC(CNC(=O)c1ccc2n(C)cc(Cc3ccc(cc3OC)C(=O)NS(=O)(=O)c3ccccc3C)c2c1)C(F)(F)F
Show InChI InChI=1S/C33H36F3N3O5S/c1-5-6-10-26(33(34,35)36)19-37-31(40)23-14-15-28-27(17-23)25(20-39(28)3)16-22-12-13-24(18-29(22)44-4)32(41)38-45(42,43)30-11-8-7-9-21(30)2/h7-9,11-15,17-18,20,26H,5-6,10,16,19H2,1-4H3,(H,37,40)(H,38,41)
PDB

UniProtKB/SwissProt

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PC cid
PC sid
UniChem

Similars
PubMed
 5n/an/an/an/an/an/an/an/a



ZENECA Pharmaceuticals Group

Curated by ChEMBL


Assay Description
Inhibition constant for displacement of [3H]-LTD4 on guinea pig lung parenchymal membranes

J Med Chem 37: 1282-97 (1994)


BindingDB Entry DOI: 10.7270/Q2SN0812
More data for this
Ligand-Target Pair