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BDBM50041359 3-[2-Methoxy-4-(toluene-2-sulfonylaminocarbonyl)-benzyl]-1-methyl-1H-indole-5-carboxylic acid (3,3,3-trifluoro-2-methyl-propyl)-amide::CHEMBL287302

SMILES: COc1cc(ccc1Cc1cn(C)c2ccc(cc12)C(=O)NCC(C)C(F)(F)F)C(=O)NS(=O)(=O)c1ccccc1C

InChI Key: InChIKey=VVGANXHBCWYQMJ-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50041359   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Cysteinyl leukotriene receptor 1


(GUINEA PIG)		BDBM50041359
PNG
(3-[2-Methoxy-4-(toluene-2-sulfonylaminocarbonyl)-b...)
Show SMILES COc1cc(ccc1Cc1cn(C)c2ccc(cc12)C(=O)NCC(C)C(F)(F)F)C(=O)NS(=O)(=O)c1ccccc1C
Show InChI InChI=1S/C30H30F3N3O5S/c1-18-7-5-6-8-27(18)42(39,40)35-29(38)22-10-9-20(26(15-22)41-4)13-23-17-36(3)25-12-11-21(14-24(23)25)28(37)34-16-19(2)30(31,32)33/h5-12,14-15,17,19H,13,16H2,1-4H3,(H,34,37)(H,35,38)
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UniProtKB/SwissProt

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PC sid
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Similars
PubMed
 12n/an/an/an/an/an/an/an/a



ZENECA Pharmaceuticals Group

Curated by ChEMBL


Assay Description
Inhibition constant for displacement of [3H]-LTD4 on guinea pig lung parenchymal membranes

J Med Chem 37: 1282-97 (1994)


BindingDB Entry DOI: 10.7270/Q2SN0812
More data for this
Ligand-Target Pair