BDBM50041512 5-Phenyl-6-thia-10b-aza-benzo[e]azulen-4-one::CHEMBL32718
SMILES: O=C1C(Sc2ccccc2-n2cccc12)c1ccccc1
InChI Key: InChIKey=NZZPYZUATMBWAV-UHFFFAOYSA-N
Data: 4 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Peripheral-Type Benzodiazepine Receptor (Rattus norvegicus (rat)) | BDBM50041512 (5-Phenyl-6-thia-10b-aza-benzo[e]azulen-4-one | CHE...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 1.23E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Napoli Curated by ChEMBL | Assay Description Displacement of [3H]-PK 11195 from rat peripheral (mitochondrial) benzodiazepine receptor | J Med Chem 37: 4100-8 (1995) BindingDB Entry DOI: 10.7270/Q2XD129C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Peripheral-Type Benzodiazepine Receptor (Rattus norvegicus (rat)) | BDBM50041512 (5-Phenyl-6-thia-10b-aza-benzo[e]azulen-4-one | CHE...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 1.22E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Siena Curated by ChEMBL | Assay Description Displacement of [3H]-PK 11195 from peripheral (mitochondrial) benzodiazepine receptor | J Med Chem 37: 1427-38 (1994) BindingDB Entry DOI: 10.7270/Q2668DVR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adenosine kinase (Homo sapiens (Human)) | BDBM50041512 (5-Phenyl-6-thia-10b-aza-benzo[e]azulen-4-one | CHE...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.30E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Universita` di Siena Curated by ChEMBL | Assay Description Inhibition of human adenosine kinase | J Med Chem 54: 1401-20 (2011) Article DOI: 10.1021/jm101438u BindingDB Entry DOI: 10.7270/Q2XD120B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Human immunodeficiency virus type 1 reverse transcriptase (Human immunodeficiency virus 1) | BDBM50041512 (5-Phenyl-6-thia-10b-aza-benzo[e]azulen-4-one | CHE...) | PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Universitá di Siena Curated by ChEMBL | Assay Description Compound was tested for Inhibition of HIV-1 RT activity. | J Med Chem 39: 2672-80 (1996) Article DOI: 10.1021/jm950702c BindingDB Entry DOI: 10.7270/Q21R6PM4 | |||||||||||
More data for this Ligand-Target Pair |