BDBM50041590 6-Phenyl-3-propyl-1,5-dihydro-pyrrolo[3,2-d]pyrimidine-2,4-dione::CHEMBL35415

SMILES: CCCn1c(=O)[nH]c2cc([nH]c2c1=O)-c1ccccc1

InChI Key: InChIKey=BPDPDYKJBCCINO-UHFFFAOYSA-N

Data: 6 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50041590   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Adenosine receptor A1 (Rattus norvegicus (rat))	BDBM50041590 (6-Phenyl-3-propyl-1,5-dihydro-pyrrolo[3,2-d]pyrimi...) Show SMILES CCCn1c(=O)[nH]c2cc([nH]c2c1=O)-c1ccccc1 Show InChI InChI=1S/C15H15N3O2/c1-2-8-18-14(19)13-12(17-15(18)20)9-11(16-13)10-6-4-3-5-7-10/h3-7,9,16H,2,8H2,1H3,(H,17,20)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	39	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Eberhard-Karls-Universität Tübingen Curated by ChEMBL					Assay Description Binding affinity to A1 adenosine receptor from rat cortical membrane in presence of [3H]-R-(phenylisopropyl)-adenosine				J Med Chem 37: 1526-34 (1994) BindingDB Entry DOI: 10.7270/Q28P5ZJN
					More data for this Ligand-Target Pair
Adenosine receptor A1 (Rattus norvegicus (rat))	BDBM50041590 (6-Phenyl-3-propyl-1,5-dihydro-pyrrolo[3,2-d]pyrimi...) Show SMILES CCCn1c(=O)[nH]c2cc([nH]c2c1=O)-c1ccccc1 Show InChI InChI=1S/C15H15N3O2/c1-2-8-18-14(19)13-12(17-15(18)20)9-11(16-13)10-6-4-3-5-7-10/h3-7,9,16H,2,8H2,1H3,(H,17,20)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	39	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Bonn Curated by ChEMBL					Assay Description Inhibition of [3H]-CCPA binding to rat adenosine A1 receptor				J Med Chem 45: 1500-10 (2002) BindingDB Entry DOI: 10.7270/Q2X929MN
					More data for this Ligand-Target Pair
Adenosine receptor A2b (Homo sapiens (Human))	BDBM50041590 (6-Phenyl-3-propyl-1,5-dihydro-pyrrolo[3,2-d]pyrimi...) Show SMILES CCCn1c(=O)[nH]c2cc([nH]c2c1=O)-c1ccccc1 Show InChI InChI=1S/C15H15N3O2/c1-2-8-18-14(19)13-12(17-15(18)20)9-11(16-13)10-6-4-3-5-7-10/h3-7,9,16H,2,8H2,1H3,(H,17,20)	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	42	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Bonn Curated by ChEMBL					Assay Description Inhibition of [3H]-ZM-241,385 binding to human adenosine A2B receptor				J Med Chem 45: 1500-10 (2002) BindingDB Entry DOI: 10.7270/Q2X929MN
					More data for this Ligand-Target Pair
Adenosine receptor A1 (Homo sapiens (Human))	BDBM50041590 (6-Phenyl-3-propyl-1,5-dihydro-pyrrolo[3,2-d]pyrimi...) Show SMILES CCCn1c(=O)[nH]c2cc([nH]c2c1=O)-c1ccccc1 Show InChI InChI=1S/C15H15N3O2/c1-2-8-18-14(19)13-12(17-15(18)20)9-11(16-13)10-6-4-3-5-7-10/h3-7,9,16H,2,8H2,1H3,(H,17,20)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	45	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Bonn Curated by ChEMBL					Assay Description Inhibition of [3H]-CCPA binding to human recombinant Adenosine A1 receptor				J Med Chem 45: 1500-10 (2002) BindingDB Entry DOI: 10.7270/Q2X929MN
					More data for this Ligand-Target Pair
Adenosine receptor A3 (Homo sapiens (Human))	BDBM50041590 (6-Phenyl-3-propyl-1,5-dihydro-pyrrolo[3,2-d]pyrimi...) Show SMILES CCCn1c(=O)[nH]c2cc([nH]c2c1=O)-c1ccccc1 Show InChI InChI=1S/C15H15N3O2/c1-2-8-18-14(19)13-12(17-15(18)20)9-11(16-13)10-6-4-3-5-7-10/h3-7,9,16H,2,8H2,1H3,(H,17,20)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	380	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Bonn Curated by ChEMBL					Assay Description Inhibition of [3H]-PSB-11 binding to human Adenosine A3 receptor				J Med Chem 45: 1500-10 (2002) BindingDB Entry DOI: 10.7270/Q2X929MN
					More data for this Ligand-Target Pair
Adenosine Receptors A2a (A2a) (Rattus norvegicus (rat))	BDBM50041590 (6-Phenyl-3-propyl-1,5-dihydro-pyrrolo[3,2-d]pyrimi...) Show SMILES CCCn1c(=O)[nH]c2cc([nH]c2c1=O)-c1ccccc1 Show InChI InChI=1S/C15H15N3O2/c1-2-8-18-14(19)13-12(17-15(18)20)9-11(16-13)10-6-4-3-5-7-10/h3-7,9,16H,2,8H2,1H3,(H,17,20)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Bonn Curated by ChEMBL					Assay Description Inhibition of [3H]-MSX-2 binding to rat adenosine A2A receptor				J Med Chem 45: 1500-10 (2002) BindingDB Entry DOI: 10.7270/Q2X929MN
					More data for this Ligand-Target Pair