BDBM50041656 CHEMBL3358442

SMILES: CCn1nccc1Oc1cc(C[C@H]2CC[C@H](O)CC2)cnc1NC(=O)NC

InChI Key: InChIKey=TVECBCSUBQOPBW-CTYIDZIISA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50041656   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glucokinase/Glucokinase regulatory protein (Homo sapiens (Human))	BDBM50041656 (CHEMBL3358442) Show SMILES CCn1nccc1Oc1cc(C[C@H]2CC[C@H](O)CC2)cnc1NC(=O)NC |r,wU:12.12,wD:15.16,(16.85,-21.56,;17.32,-20.09,;18.83,-19.78,;19.97,-20.81,;21.31,-20.03,;20.98,-18.53,;19.45,-18.37,;18.68,-17.03,;17.14,-17.03,;16.37,-18.37,;14.83,-18.37,;14.06,-19.7,;12.52,-19.7,;11.75,-21.04,;10.21,-21.04,;9.44,-19.7,;7.9,-19.7,;10.21,-18.37,;11.75,-18.37,;14.06,-17.03,;14.83,-15.7,;16.37,-15.7,;17.14,-14.36,;16.37,-13.04,;17.14,-11.7,;14.83,-13.04,;14.06,-14.36,)| Show InChI InChI=1S/C19H27N5O3/c1-3-24-17(8-9-22-24)27-16-11-14(10-13-4-6-15(25)7-5-13)12-21-18(16)23-19(26)20-2/h8-9,11-13,15,25H,3-7,10H2,1-2H3,(H2,20,21,23,26)/t13-,15-	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	68	n/a	n/a	n/a	n/a
Amgen, Inc. Curated by ChEMBL					Assay Description Activation of human recombinant Glucokinase measured over 5 mins by G6-PD coupled assay in presence of 5 mM glucose				ACS Med Chem Lett 5: 1284-9 (2014) Article DOI: 10.1021/ml500341w BindingDB Entry DOI: 10.7270/Q2KD20JZ
					More data for this Ligand-Target Pair