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BDBM50041853 3-Cyclopentyloxy-N-(3,5-dichloro-1-oxy-pyridin-4-yl)-4-methoxy-benzamide::CHEMBL45395

SMILES: COc1ccc(cc1OC1CCCC1)C(=O)Nc1c(Cl)c[n+]([O-])cc1Cl

InChI Key: InChIKey=IOHIGXZNGBFEFK-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50041853   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Phosphodiesterase 4A


(Sus scrofa)		BDBM50041853
PNG
(3-Cyclopentyloxy-N-(3,5-dichloro-1-oxy-pyridin-4-y...)
Show SMILES COc1ccc(cc1OC1CCCC1)C(=O)Nc1c(Cl)c[n+]([O-])cc1Cl
Show InChI InChI=1S/C18H18Cl2N2O4/c1-25-15-7-6-11(8-16(15)26-12-4-2-3-5-12)18(23)21-17-13(19)9-22(24)10-14(17)20/h6-10,12H,2-5H2,1H3,(H,21,23)
UniProtKB/TrEMBL

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PC sid
UniChem

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PubMed
n/an/a 2n/an/an/an/an/an/a



Rhône-Poulenc Rorer Central Research

Curated by ChEMBL


Assay Description
Inhibitory potency against pig aortic PDE IV

J Med Chem 37: 1696-703 (1994)


BindingDB Entry DOI: 10.7270/Q2CF9P5F
More data for this
Ligand-Target Pair