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SMILES: COc1ccc(cc1OC1CCCC1)C(=O)Nc1c(C)nsc1C#N

InChI Key: InChIKey=YYGIANNEIXMOQM-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50041864   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
3',5'-cyclic-AMP phosphodiesterase


(Sus scrofa)		BDBM50041864
PNG
(CHEMBL47288 | N-(5-Cyano-3-methyl-isothiazol-4-yl)...)
Show SMILES COc1ccc(cc1OC1CCCC1)C(=O)Nc1c(C)nsc1C#N
Show InChI InChI=1S/C18H19N3O3S/c1-11-17(16(10-19)25-21-11)20-18(22)12-7-8-14(23-2)15(9-12)24-13-5-3-4-6-13/h7-9,13H,3-6H2,1-2H3,(H,20,22)
UniProtKB/TrEMBL

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PubMed
n/an/a 200n/an/an/an/an/an/a



Rhône-Poulenc Rorer Central Research

Curated by ChEMBL


Assay Description
Inhibitory potency against pig aortic PDE IV

J Med Chem 37: 1696-703 (1994)


BindingDB Entry DOI: 10.7270/Q2CF9P5F
More data for this
Ligand-Target Pair