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SMILES: Cc1sc2nc(N)nc(N)c2c1Cc1ccccc1

InChI Key: InChIKey=UBEKRQCLVPLZMA-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50041937   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dihydrofolate reductase (Lactobacillus casei)	BDBM50041937 (5-Benzyl-6-methyl-thieno[2,3-d]pyrimidine-2,4-diam...) Show SMILES Cc1sc2nc(N)nc(N)c2c1Cc1ccccc1 Show InChI InChI=1S/C14H14N4S/c1-8-10(7-9-5-3-2-4-6-9)11-12(15)17-14(16)18-13(11)19-8/h2-6H,7H2,1H3,(H4,15,16,17,18)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Harvard Medical School Curated by ChEMBL					Assay Description Tested for inhibitory activity against dihydrofolate reductase in L. casei				J Med Chem 36: 3103-12 (1993) BindingDB Entry DOI: 10.7270/Q23X85PX
					More data for this Ligand-Target Pair
Dihydrofolate reductase (Escherichia coli)	BDBM50041937 (5-Benzyl-6-methyl-thieno[2,3-d]pyrimidine-2,4-diam...) Show SMILES Cc1sc2nc(N)nc(N)c2c1Cc1ccccc1 Show InChI InChI=1S/C14H14N4S/c1-8-10(7-9-5-3-2-4-6-9)11-12(15)17-14(16)18-13(11)19-8/h2-6H,7H2,1H3,(H4,15,16,17,18)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Harvard Medical School Curated by ChEMBL					Assay Description Inhibition of dihydrofolate reductase in pneumocystis carinii.				J Med Chem 36: 3103-12 (1993) BindingDB Entry DOI: 10.7270/Q23X85PX
					More data for this Ligand-Target Pair
Dihydrofolate reductase (Lactobacillus casei)	BDBM50041937 (5-Benzyl-6-methyl-thieno[2,3-d]pyrimidine-2,4-diam...) Show SMILES Cc1sc2nc(N)nc(N)c2c1Cc1ccccc1 Show InChI InChI=1S/C14H14N4S/c1-8-10(7-9-5-3-2-4-6-9)11-12(15)17-14(16)18-13(11)19-8/h2-6H,7H2,1H3,(H4,15,16,17,18)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.90E+4	n/a	n/a	n/a	n/a	n/a	n/a
Harvard Medical School Curated by ChEMBL					Assay Description Tested for inhibitory activity against dihydrofolate reductase in Beef liver				J Med Chem 36: 3103-12 (1993) BindingDB Entry DOI: 10.7270/Q23X85PX
					More data for this Ligand-Target Pair
Dihydrofolate reductase (Escherichia coli)	BDBM50041937 (5-Benzyl-6-methyl-thieno[2,3-d]pyrimidine-2,4-diam...) Show SMILES Cc1sc2nc(N)nc(N)c2c1Cc1ccccc1 Show InChI InChI=1S/C14H14N4S/c1-8-10(7-9-5-3-2-4-6-9)11-12(15)17-14(16)18-13(11)19-8/h2-6H,7H2,1H3,(H4,15,16,17,18)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Harvard Medical School Curated by ChEMBL					Assay Description Tested for inhibitory activity against dihydrofolate reductase in Beef liver				J Med Chem 36: 3103-12 (1993) BindingDB Entry DOI: 10.7270/Q23X85PX
					More data for this Ligand-Target Pair
Dihydrofolate reductase (Rattus norvegicus (rat))	BDBM50041937 (5-Benzyl-6-methyl-thieno[2,3-d]pyrimidine-2,4-diam...) Show SMILES Cc1sc2nc(N)nc(N)c2c1Cc1ccccc1 Show InChI InChI=1S/C14H14N4S/c1-8-10(7-9-5-3-2-4-6-9)11-12(15)17-14(16)18-13(11)19-8/h2-6H,7H2,1H3,(H4,15,16,17,18)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>3.70E+4	n/a	n/a	n/a	n/a	n/a	n/a
Harvard Medical School Curated by ChEMBL					Assay Description Inhibition of rat liver dihydrofolate reductase.				J Med Chem 36: 3103-12 (1993) BindingDB Entry DOI: 10.7270/Q23X85PX
					More data for this Ligand-Target Pair