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BDBM50042067 1-Butyl-4-hydroxy-2-oxo-1,2-dihydro-quinoline-3-carboxylic acid (8-methyl-8-aza-bicyclo[3.2.1]oct-3-yl)-amide::CHEMBL320480

SMILES: CCCCn1c2ccccc2c(O)c(C(=O)NC2CC3CCC(C2)N3C)c1=O

InChI Key: InChIKey=WGDQFZMBDVNRCW-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50042067   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Serotonin 3a (5-HT3a)/3b (5-HT3b) receptor


(Rattus norvegicus-RAT)		BDBM50042067
PNG
(1-Butyl-4-hydroxy-2-oxo-1,2-dihydro-quinoline-3-ca...)
Show SMILES CCCCn1c2ccccc2c(O)c(C(=O)NC2CC3CCC(C2)N3C)c1=O |TLB:16:17:24:20.21|
Show InChI InChI=1S/C22H29N3O3/c1-3-4-11-25-18-8-6-5-7-17(18)20(26)19(22(25)28)21(27)23-14-12-15-9-10-16(13-14)24(15)2/h5-8,14-16,26H,3-4,9-13H2,1-2H3,(H,23,27)
PDB

UniProtKB/SwissProt

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PC cid
PC sid
UniChem

Similars
PubMed
 0.480n/an/an/an/an/an/an/an/a



Kyowa Hakko Kogyo Company, Ltd.

Curated by ChEMBL


Assay Description
Binding affinity against radioligand [3H]quipazine labeled 5-hydroxytryptamine 3 receptor sites in neuroblastoma-glioma (NG108-15) cells.

J Med Chem 36: 617-26 (1993)


BindingDB Entry DOI: 10.7270/Q25B034N
More data for this
Ligand-Target Pair