BDBM50042225 4'-(4-Oxo-2-pentyl-1,3-diaza-spiro[4.4]non-1-en-3-ylmethyl)-biphenyl-2-carboxylic acid::CHEMBL114267

SMILES: CCCCCC1=NC2(CCCC2)C(=O)N1Cc1ccc(cc1)-c1ccccc1C(O)=O

InChI Key: InChIKey=NODORMDBKPDUBB-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50042225   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Angiotensin II AT1B (RAT)	BDBM50042225 (4'-(4-Oxo-2-pentyl-1,3-diaza-spiro[4.4]non-1-en-3-...) Show SMILES CCCCCC1=NC2(CCCC2)C(=O)N1Cc1ccc(cc1)-c1ccccc1C(O)=O |t:5| Show InChI InChI=1S/C26H30N2O3/c1-2-3-4-11-23-27-26(16-7-8-17-26)25(31)28(23)18-19-12-14-20(15-13-19)21-9-5-6-10-22(21)24(29)30/h5-6,9-10,12-15H,2-4,7-8,11,16-18H2,1H3,(H,29,30)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	24	n/a	n/a	n/a	n/a	n/a	n/a
Sanofi Recherche Curated by ChEMBL					Assay Description Binding affinity for Angiotensin II receptor, type 1 measured by ability to displace [125I]- A II from its specific binding site in rat liver membran...				J Med Chem 36: 3371-80 (1993) BindingDB Entry DOI: 10.7270/Q22Z14M0
					More data for this Ligand-Target Pair